MicroRNA in United Airway Diseases

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2016 May 18

PMID 27187364

Citations 14

Authors

Zheng Liu

Xin-Hao Zhang

Borja Callejas-Diaz

Joaquim Mullol

Affiliations

Soon will be listed here.

Abstract

The concept of united airway diseases (UAD) has received increasing attention in recent years. Sustained and increased inflammation is a common feature of UAD, which is inevitably accompanied with marked gene modification and tight gene regulation. However, gene regulation in the common inflammatory processes in UAD remains unclear. MicroRNA (miRNA), a novel regulator of gene expression, has been considered to be involved in many inflammatory diseases. Although there are an increasing number of studies of miRNAs in inflammatory upper and lower airway diseases, few miRNAs have been identified that directly link the upper and lower airways. In this article, therefore, we reviewed the relevant studies available in order to improve the understanding of the roles of miRNAs in the interaction and pathogenesis of UAD.

Citing Articles

Causal associations between pediatric asthma and united airways disease: a two-sample Mendelian randomization analysis.

Gao T, Cai Q, Hu S, Zhu R, Wang J Front Med (Lausanne). 2024; 11:1369695.

PMID: 38919942 PMC: 11196945. DOI: 10.3389/fmed.2024.1369695.

miR-224-5p Attenuates Allergic Responses in Mice with Allergic Rhinitis by Modulating the Th1/Th2 Response.

Li Y, An R, Wu M, He J, He X Anal Cell Pathol (Amst). 2024; 2024:5531970.

PMID: 38455868 PMC: 10919974. DOI: 10.1155/2024/5531970.

Evaluation of probe-based ultra-sensitive detection of miRNA using a single-molecule fluorescence imaging method: miR-126 used as the model.

Liu L, Wang X, Li Y, Liu J Front Bioeng Biotechnol. 2023; 11:1081488.

PMID: 36761298 PMC: 9902880. DOI: 10.3389/fbioe.2023.1081488.

Predicting Pseudogene-miRNA Associations Based on Feature Fusion and Graph Auto-Encoder.

Zhou S, Sun W, Zhang P, Li L Front Genet. 2021; 12:781277.

PMID: 34966413 PMC: 8710693. DOI: 10.3389/fgene.2021.781277.

Visualization of microRNA-21 Dynamics in Neuroblastoma Using Magnetic Resonance Imaging Based on a microRNA-21-Responsive Reporter Gene.

Bao G, Sun J, Zheng H, Hou J, Huang J, Wei J Front Oncol. 2021; 11:747305.

PMID: 34804934 PMC: 8602822. DOI: 10.3389/fonc.2021.747305.

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