Determination of 50% Endpoint Titer Using a Simple Formula

Overview

Journal World J Virol

Publisher Baishideng Publishing Group

Date 2016 May 14

PMID 27175354

Citations 354

Authors

Muthannan Andavar Ramakrishnan

Affiliations

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Abstract

Two commonly used methods for calculating 50% endpoint using serial dilutions are Spearman-Karber method and Reed and Muench method. To understand/apply the above formulas, moderate statistical/mathematical skills are necessary. In this paper, a simple formula/method for calculating 50% endpoints has been proposed. The formula yields essentially similar results as those of the Spearman-Karber method. The formula has been rigorously evaluated with several samples.

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