Diagnosis of Tuberculosis Based on the Detection of a Cocktail of Mycobacterial Antigen 85B, ESAT-6 and Cord Factor by Immuno-PCR

Overview

Journal J Microbiol Methods

Specialty Microbiology

Date 2016 May 11

PMID 27164021

Citations 3

Authors

Promod K Mehta

Netrapal Singh

Renu Dharra

Bhawna Dahiya

Suman Sharma

Abhishek Sheoran

Krishna B Gupta

Dhruva Chaudhary

Neeru Mehta

Mandira Varma-Basil

Affiliations

Soon will be listed here.

Abstract

Attempts were made to enhance the sensitivity of immuno-PCR assay based on the detection of cocktail of mycobacterial antigen 85B (Rv1886c), ESAT-6 (Rv3875) and cord factor (trehalose 6,6'-dimycolate) in pulmonary and extrapulmonary TB patients. Detection of Ag85B was found to be superior to the detection of cocktail in TB patients.

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