Merkel Cell Carcinoma: a Review

Overview

Journal Cutis

Specialty Dermatology

Date 2016 May 11

PMID 27163912

Citations 4

Authors

Christian W Oram

Cynthia L Bartus

Stephen M Purcell

Affiliations

Soon will be listed here.

Abstract

Merkel cell carcinoma (MCC) is a rare neuroendocrine tumor of unknown origin that usually presents in the elderly population. A novel polyomavirus has been associated with a large percentage of tumors. Immune response plays an important role in pathogenesis of MCC. This article reviews the history, pathogenesis, presentation, and treatment of MCC. Future treatments also are discussed briefly.

Citing Articles

MicroRNAs as Potential Biomarkers in Merkel Cell Carcinoma.

Konstatinell A, Coucheron D, Sveinbjornsson B, Moens U Int J Mol Sci. 2018; 19(7).

PMID: 29949882 PMC: 6073391. DOI: 10.3390/ijms19071873.

Living with Merkel Cell Carcinoma (MCC): Development of a Conceptual Model of MCC Based on Patient Experiences.

Kaufman H, Dias Barbosa C, Guillemin I, Lambert J, Mahnke L, Bharmal M Patient. 2018; 11(4):439-449.

PMID: 29512061 PMC: 6019419. DOI: 10.1007/s40271-018-0301-0.

Reduced H3K27me3 expression in Merkel cell polyoma virus-positive tumors.

Busam K, Pulitzer M, Coit D, Arcila M, Leng D, Jungbluth A Mod Pathol. 2017; 30(6):877-883.

PMID: 28281550 PMC: 5451312. DOI: 10.1038/modpathol.2017.8.

[Merkel cell carcinoma of the eyelid. An often unrecognized tumor entity : Clinical aspects and treatment strategies].

Hoerster R, Schlaak M, Koch K, Ortmann M, Mauch C, Heindl L Ophthalmologe. 2016; 114(2):134-139.

PMID: 27651329 DOI: 10.1007/s00347-016-0355-0.