Host Immune Cellular Reactions in Corneal Neovascularization

Overview

Journal Int J Ophthalmol

Specialty Ophthalmology

Date 2016 May 11

PMID 27162740

Citations 10

Authors

Nizar S Abdelfattah

Mohamed Amgad

Amira A Zayed

Affiliations

Soon will be listed here.

Abstract

Corneal neovascularization (CNV) is a global important cause of visual impairment. The immune mechanisms leading to corneal heme- and lymphangiogenesis have been extensively studied over the past years as more attempts were made to develop better prophylactic and therapeutic measures. This article aims to discuss immune cells of particular relevance to CNV, with a focus on macrophages, Th17 cells, dendritic cells and the underlying immunology of common pathologies involving neovascularization of the cornea. Hopefully, a thorough understanding of these topics would propel the efforts to halt the detrimental effects of CNV.

Citing Articles

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Detailed protocol for a corneal thermal cauterization-based (lymph-)angiogenesis assay in mice.

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