Current Approaches of Photothermal Therapy in Treating Cancer Metastasis with Nanotherapeutics

Overview

Journal Theranostics

Date 2016 May 11

PMID 27162548

Citations 215

Authors

Lili Zou

Hong Wang

Bin He

Lijuan Zeng

Tao Tan

Haiqiang Cao

Xinyu He

Zhiwen Zhang

Shengrong Guo

Yaping Li

Affiliations

Soon will be listed here.

Abstract

Cancer metastasis accounts for the high mortality of many types of cancer. Owing to the unique advantages of high specificity and minimal invasiveness, photothermal therapy (PTT) has been evidenced with great potential in treating cancer metastasis. In this review, we outline the current approaches of PTT with respect to its application in treating metastatic cancer. PTT can be used alone, guided with multimodal imaging, or combined with the current available therapies for effective treatment of cancer metastasis. Numerous types of photothermal nanotherapeutics (PTN) have been developed with encouraging therapeutic efficacy on metastatic cancer in many preclinical animal experiments. We summarize the design and performance of various PTN in PTT alone and their combinational therapy. We also point out the lacking area and the most promising approaches in this challenging field. In conclusion, PTT or their combinational therapy can provide an essential promising therapeutic modality against cancer metastasis.

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