Diagnostic Value of F-18 FDG PET/CT in Patients with Spondylodiscitis: Is Dual Time Point Imaging Time Worthy?

Overview

Journal Diagn Microbiol Infect Dis

Specialties Infectious Diseases
Microbiology
Pathology

Date 2016 May 11

PMID 27160950

Citations 6

Authors

Burcak Yilmaz Gunes

Cetin Onsel

Kerim Sonmezoglu

Resat Ozaras

Metin Halac

Fehmi Tabak

Sait Sager

Bilgul Mete

Haluk Sayman

Bedii Kanmaz

Affiliations

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Abstract

Purpose: In this retrospective study, we aimed to investigate the value of FDG-PET/CT in the diagnosis of spondylodiscitis (SD), the significance of dual time point imaging (DTPI) for SD diagnosis and the worth of SUVmax data for distinguishing tuberculous vs. non-tuberculous SD.

Materials And Methods: 32 patients with suspected SD were scanned with FDG-PET/CT. For quantitative analysis maximum standardized uptake value (SUVmax) of the lesion area was measured. Nineteen patients had DTPI of FDG-PET/CT. The final diagnoses were achieved by histopathological, microbiological, and clinical results.

Results: Specific pathogens were isolated in 21 patients; other patients were accepted as nonspecific bacterial SD. In all patients, FDG-PET/CT results were compatible with SD diagnosis. The SUVmax data for tuberculous and non-tuberculous SD and DTPI results were statistically insignificant.

Conclusion: FDG-PET/CT is a successful modality for SD diagnosis; additionally, DTPI protocol for FDG-PET/CT in SD diagnosis and SUVmax data for differentiation between non-tbc SD and tbc SD are useless.

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