Vaccine Hesitancy: More Than a Movement

Overview

Journal Hum Vaccin Immunother

Specialty Allergy & Immunology

Date 2016 May 10

PMID 27159558

Citations 38

Authors

David Callender

Affiliations

Soon will be listed here.

Abstract

Vaccines are some of if not the most successful public health endeavors ever put into practice. Countless lives have been saved and the occurrences of vaccine preventable diseases are at a fraction of the rate experienced before vaccines. Vaccines and the realization of their compulsory scheduling are highly studied, safe, and purposeful. Despite these realities, there are an alarming number of parents who do not permit the vaccination of their children as scheduled. This is known in the health community as vaccine hesitancy and commonly portrayed in popular media as anti-vaccination sediment. This analysis opens with the topic as it was addressed during a September 2015 debate for the Republic Party's 2016 presidential nomination. Some key historical aspects of vaccine hesitancy are presented. This history leads to a description of the 2014-2015 measles outbreak in California. The factors that aide in the recruitment of under vaccination are then explored. Finally, select strategies to control, combat, and potentially attenuate vaccine hesitancy are presented.

Citing Articles

Global vaccine research and application hotspots and trends: a systematic bibliometric analysis based on SCIE highly cited papers.

Shi R, Cao H, He M, Wang Y, Zhu Y, Wang X BMJ Open. 2025; 15(1):e094935.

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Online Media Use and COVID-19 Vaccination in Real-World Personal Networks: Quantitative Study.

Oana I, Hancean M, Perc M, Lerner J, Mihaila B, Geanta M J Med Internet Res. 2024; 26:e58257.

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COVID-19 vaccine uptake among people with HIV: identifying characteristics associated with vaccine hesitancy.

Boschung K, Gill M, Krentz H, Dalere J, Beckthold B, Fonseca K Sci Rep. 2023; 13(1):20610.

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Determinants of COVID-19 vaccine readiness and hesitancy among adults in sub-Saharan Africa.

Abubakari S, Workneh F, Asante K, Hemler E, Madzorera I, Wang D PLOS Glob Public Health. 2023; 3(7):e0000713.

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General publics' perception toward COVID-19 vaccines in Afghanistan, 2021.

Hakim M, Mansoor G, Walizada A, Saeed K, Naeemi S, Fazil F Hum Vaccin Immunother. 2023; 19(2):2228164.

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References

Maglione M, Das L, Raaen L, Smith A, Chari R, Newberry S . Safety of vaccines used for routine immunization of U.S. children: a systematic review. Pediatrics. 2014; 134(2):325-37. DOI: 10.1542/peds.2014-1079. View

Zhou F, Shefer A, Wenger J, Messonnier M, Wang L, Lopez A . Economic evaluation of the routine childhood immunization program in the United States, 2009. Pediatrics. 2014; 133(4):577-85. DOI: 10.1542/peds.2013-0698. View

Mariner W, Annas G, Glantz L . Jacobson v Massachusetts: it's not your great-great-grandfather's public health law. Am J Public Health. 2005; 95(4):581-90. PMC: 1449224. DOI: 10.2105/AJPH.2004.055160. View

Fombonne E, Chakrabarti S . No evidence for a new variant of measles-mumps-rubella-induced autism. Pediatrics. 2001; 108(4):E58. DOI: 10.1542/peds.108.4.e58. View

Gross L . A broken trust: lessons from the vaccine--autism wars. PLoS Biol. 2009; 7(5):e1000114. PMC: 2682483. DOI: 10.1371/journal.pbio.1000114. View

Siddiqui M, Salmon D, Omer S . Epidemiology of vaccine hesitancy in the United States. Hum Vaccin Immunother. 2013; 9(12):2643-8. PMC: 4162046. DOI: 10.4161/hv.27243. View

Omer S, Richards J, Ward M, Bednarczyk R . Vaccination policies and rates of exemption from immunization, 2005-2011. N Engl J Med. 2012; 367(12):1170-1. PMC: 9993615. DOI: 10.1056/NEJMc1209037. View

Jones M, Buttenheim A . Potential effects of California's new vaccine exemption law on the prevalence and clustering of exemptions. Am J Public Health. 2014; 104(9):e3-6. PMC: 4151919. DOI: 10.2105/AJPH.2014.302065. View

Offit P, Moser C . The problem with Dr Bob's alternative vaccine schedule. Pediatrics. 2009; 123(1):e164-9. DOI: 10.1542/peds.2008-2189. View

10.

Rathbone J . Lady Mary Wortley Montague's contribution to the eradication of smallpox. Lancet. 1996; 347(9014):1566. DOI: 10.1016/s0140-6736(96)90724-2. View

11.

Kata A . Anti-vaccine activists, Web 2.0, and the postmodern paradigm--an overview of tactics and tropes used online by the anti-vaccination movement. Vaccine. 2011; 30(25):3778-89. DOI: 10.1016/j.vaccine.2011.11.112. View

12.

Gowda C, Dempsey A . The rise (and fall?) of parental vaccine hesitancy. Hum Vaccin Immunother. 2013; 9(8):1755-62. PMC: 3906278. DOI: 10.4161/hv.25085. View

13.

Riedel S . Edward Jenner and the history of smallpox and vaccination. Proc (Bayl Univ Med Cent). 2005; 18(1):21-5. PMC: 1200696. DOI: 10.1080/08998280.2005.11928028. View

14.

Brown K, Kroll J, Hudson M, Ramsay M, Green J, Vincent C . Omission bias and vaccine rejection by parents of healthy children: implications for the influenza A/H1N1 vaccination programme. Vaccine. 2010; 28(25):4181-5. DOI: 10.1016/j.vaccine.2010.04.012. View

15.

Wakefield A, Murch S, Anthony A, Linnell J, Casson D, Malik M . Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet. 1998; 351(9103):637-41. DOI: 10.1016/s0140-6736(97)11096-0. View

16.

Zipprich J, Winter K, Hacker J, Xia D, Watt J, Harriman K . Measles outbreak--California, December 2014-February 2015. MMWR Morb Mortal Wkly Rep. 2015; 64(6):153-4. PMC: 4584705. View

17.

Fine P . Herd immunity: history, theory, practice. Epidemiol Rev. 1993; 15(2):265-302. DOI: 10.1093/oxfordjournals.epirev.a036121. View

18.

Buttenheim A, Jones M, Baras Y . Exposure of California kindergartners to students with personal belief exemptions from mandated school entry vaccinations. Am J Public Health. 2012; 102(8):e59-67. PMC: 3464858. DOI: 10.2105/AJPH.2012.300821. View

19.

Jacobson R, St Sauver J, Finney Rutten L . Vaccine Hesitancy. Mayo Clin Proc. 2015; 90(11):1562-8. DOI: 10.1016/j.mayocp.2015.09.006. View

20.

Salmon D, Teret S, MacIntyre C, Salisbury D, Burgess M, Halsey N . Compulsory vaccination and conscientious or philosophical exemptions: past, present, and future. Lancet. 2006; 367(9508):436-42. DOI: 10.1016/S0140-6736(06)68144-0. View