The Diagnostic Approach to Central Adrenocortical Insufficiency (CAI) in Thalassemia

Overview

Journal Mediterr J Hematol Infect Dis

Specialty Infectious Diseases

Date 2016 May 10

PMID 27158439

Citations 3

Authors

Vincenzo De Sanctis

Heba Elsedfy

Ashraf T Soliman

Ihab Zaki Elhakim

Nada A Soliman

Mehran Karimi

Rania Elalaily

Affiliations

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Citing Articles

Adrenal Insufficiency in Patients with Beta Thalassemia: A Meta-Analysis.

Savvidis C, Ragia D, Delicou S, Xydaki A, Rizzo M, Ilias I Medicina (Kaunas). 2024; 60(10).

PMID: 39459358 PMC: 11509364. DOI: 10.3390/medicina60101571.

Mammosomatotroph and mixed somatotroph-lactotroph adenoma in acromegaly: a retrospective study with long-term follow-up.

Lv L, Jiang Y, Yin S, Hu Y, Chen C, Ma W Endocrine. 2019; 66(2):310-318.

PMID: 31368083 DOI: 10.1007/s12020-019-02029-1.

The ICET-A Survey on Current Criteria Used by Clinicians for the Assessment of Central Adrenal Insufficiency in Thalassemia: Analysis of Results and Recommendations.

De Sanctis V, Soliman A, Elsedfy H, Albu A, Al Jaouni S, Al Yaarubi S Mediterr J Hematol Infect Dis. 2016; 8(1):e2016034.

PMID: 27413526 PMC: 4928531. DOI: 10.4084/MJHID.2016.034.

References

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Huang K, Mittelman S, Coates T, Geffner M, Wood J . A significant proportion of thalassemia major patients have adrenal insufficiency detectable on provocative testing. J Pediatr Hematol Oncol. 2014; 37(1):54-9. PMC: 4393555. DOI: 10.1097/MPH.0000000000000199. View

De Sanctis V, Soliman A, Yassin M, Garofalo P . Cortisol levels in central adrenal insufficiency: light and shade. Pediatr Endocrinol Rev. 2015; 12(3):283-9. View

Elsedfy H, El Kholy M, Hamza R, Hamed A, Elalfy M . Adrenal function in thalassemia major adolescents. Pediatr Endocrinol Rev. 2011; 8 Suppl 2:295-9. View

De Sanctis V, Elsedfy H, Soliman A, Elhakim I, Pepe A, Kattamis C . Acquired Hypogonadotropic Hypogonadism (AHH) in Thalassaemia Major Patients: An Underdiagnosed Condition?. Mediterr J Hematol Infect Dis. 2016; 8(1):e2016001. PMC: 4696472. DOI: 10.4084/MJHID.2016.001. View

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De Sanctis V, Soliman A, Candini G, Campisi S, Anastasi S, Iassin M . High prevalence of central hypothyroidism in adult patients with β-thalassemia major. Georgian Med News. 2013; (222):88-94. View

Srivatsa A, Marwaha R, Muraldharan R, Trehan A . Assessment of adrenal endocrine function in Asian thalassemics. Indian Pediatr. 2005; 42(1):31-5. View

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Ucar A, Oner N, Ozek G, Cetincakmak M, Abuhandan M, Yildirim A . Evaluation of the glucocorticoid, mineralocorticoid, and adrenal androgen secretion dynamics in a large cohort of patients aged 6-18 years with transfusion-dependent β-thalassemia major, with an emphasis on the impact of cardiac iron load. Endocrine. 2016; 53(1):240-8. DOI: 10.1007/s12020-016-0872-2. View

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Soliman A, Al Yafei F, Al-Naimi L, Almarri N, Sabt A, Yassin M . Longitudinal study on thyroid function in patients with thalassemia major: High incidence of central hypothyroidism by 18 years. Indian J Endocrinol Metab. 2014; 17(6):1090-5. PMC: 3872691. DOI: 10.4103/2230-8210.122635. View

12.

Soliman A, De Sanctis V, Elsedfy H, Yassin M, Skordis N, Karimi M . Growth hormone deficiency in adults with thalassemia: an overview and the I-CET recommendations. Georgian Med News. 2013; (222):79-88. View

13.

Hamrahian A, Yuen K, Gordon M, Pulaski-Liebert K, Bena J, Biller B . Revised GH and cortisol cut-points for the glucagon stimulation test in the evaluation of GH and hypothalamic-pituitary-adrenal axes in adults: results from a prospective randomized multicenter study. Pituitary. 2016; 19(3):332-41. DOI: 10.1007/s11102-016-0712-7. View