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DyNet: Visualization and Analysis of Dynamic Molecular Interaction Networks

Overview
Journal Bioinformatics
Publisher Oxford University Press
Specialty Biology
Date 2016 May 7
PMID 27153624
Citations 66
Authors
Ivan H Goenawan
Kenneth Bryan
David J Lynn
Affiliations
Soon will be listed here.
Abstract

Unlabelled: : The ability to experimentally determine molecular interactions on an almost proteome-wide scale under different conditions is enabling researchers to move from static to dynamic network analysis, uncovering new insights into how interaction networks are physically rewired in response to different stimuli and in disease. Dynamic interaction data presents a special challenge in network biology. Here, we present DyNet, a Cytoscape application that provides a range of functionalities for the visualization, real-time synchronization and analysis of large multi-state dynamic molecular interaction networks enabling users to quickly identify and analyze the most 'rewired' nodes across many network states.

Availability And Implementation: DyNet is available at the Cytoscape (3.2+) App Store (http://apps.cytoscape.org/apps/dynet).

Contact: david.lynn@sahmri.com

Supplementary Information: Supplementary data are available at Bioinformatics online.

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