Salivary Markers for Periodontal and General Diseases

Overview

Journal Dis Markers

Publisher Wiley

Specialty Biochemistry

Date 2016 May 5

PMID 27143814

Citations 25

Authors

Stepan Podzimek

Lucie Vondrackova

Jana Duskova

Tatjana Janatova

Zdenek Broukal

Affiliations

Soon will be listed here.

Abstract

The determination of biomarkers in saliva is becoming an important part of laboratory diagnostics and the prediction of not only periodontal, but also other tissue and organ diseases. Biomarkers in saliva (e.g., enzymes, protein markers, or oxidative stress markers) can be used for activity determination and for periodontal disease prognosis. Saliva also contains many markers which can predict the risk of certain diseases (e.g., diabetes mellitus, cardiovascular, oncology, endocrinology, and psychiatric diseases). The study of salivary components proteomics clearly shows the relationship of periodontal diseases and diseases of distant systems, organs, or tissues.

Citing Articles

Variability of salivary analytes under daily conditions and their implications for periodontitis biomarkers.

Rocha A, Orlandini R, Motta A, Pinheiro J, Silva G, Oliveira V Front Dent Med. 2025; 5:1369186.

PMID: 39917715 PMC: 11797852. DOI: 10.3389/fdmed.2024.1369186.

Gingival Enlargement Associated with Orthodontics Appliance Increases Protein Carbonylation and Alters Phosphorylation of Salivary Proteome.

Lopez Arrieta Z, Rodriguez-Cavallo E, Mendez-Cuadro D Dent J (Basel). 2024; 12(7).

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Evaluating and optimizing Acid-pH and Direct Lysis RNA extraction for SARS-CoV-2 RNA detection in whole saliva.

LaBute B, Fong J, Ziaee F, Gombar R, Stover M, Beaudin T Sci Rep. 2024; 14(1):7017.

PMID: 38527999 PMC: 10963802. DOI: 10.1038/s41598-024-54183-w.

Systematic review and meta-analysis of the antioxidant capacity of lycopene in the treatment of periodontal disease.

Lopez-Valverde N, Lopez-Valverde A, Macedo de Sousa B, Blanco Rueda J Front Bioeng Biotechnol. 2024; 11:1309851.

PMID: 38344076 PMC: 10857001. DOI: 10.3389/fbioe.2023.1309851.

Frequency and association of Epstein-Barr Virus genotype in rheumatoid arthritis patients of Khyber Pakhtunkhwa, Pakistan.

Munir A, Khan S, Khan S, Attaullah S, Munir M, Saleem A PLoS One. 2023; 18(12):e0295124.

PMID: 38117833 PMC: 10732363. DOI: 10.1371/journal.pone.0295124.

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