MicroRNA Therapeutics: Discovering Novel Targets and Developing Specific Therapy

Overview

Journal Perspect Clin Res

Specialty General Medicine

Date 2016 May 4

PMID 27141472

Citations 206

Authors

Ajay Francis Christopher

Raman Preet Kaur

Gunpreet Kaur

Amandeep Kaur

Vikas Gupta

Parveen Bansal

Affiliations

Soon will be listed here.

Abstract

MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression in diverse biological process. They act as intracellular mediators that are necessary for various biological processes. MicroRNAs targeting pathways of human disease provide a new and potential powerful candidate for therapeutic intervention against various pathological conditions. Even though, the information about miRNA biology has significantly enriched but we still do not completely understand the mechanism of miRNA gene regulation. Various groups across the globe and pharmaceutical companies are conducting research and developments to explore miRNA based therapy and build a whole new area of miroRNA therapeutics. Consequently, few miRNAs have entered the preclinical and clinical stage and soon might be available in the market for use in humans.

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