Diffusion Tensor Imaging in the Normal Breast: Influences of Fibroglandular Tissue Composition and Background Parenchymal Enhancement

Overview

Journal Clin Imaging

Publisher Elsevier

Specialty Radiology

Date 2016 May 3

PMID 27133695

Citations 8

Authors

Michael Jonathan Plaza

Elizabeth A Morris

Sunitha B Thakur

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate effects of fibroglandular tissue (FGT) composition and background parenchymal enhancement (BPE) on diffusion tensor imaging (DTI) parameters in normal breast tissue.

Methods: DTI analysis was performed on 35 breasts with regions of interest drawn to include only normal tissue. Breasts were dichotomized by FGT composition and by BPE; DTI parameters were compared.

Results: The λ1 principal diffusion coefficient was lower in breasts with moderate/marked BPE versus those with minimal/mild BPE (P=.039). All other parameters were unaffected.

Conclusion: λ1 is sensitive to differences in BPE within normal breast tissue that should be taken into account in DTI evaluation.

Citing Articles

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