Differential Profiles in Auditory Social Cognition Deficits Between Adults with Autism and Schizophrenia Spectrum Disorders: A Preliminary Analysis

Overview

Journal J Psychiatr Res

Specialty Psychiatry

Date 2016 May 2

PMID 27131617

Citations 11

Authors

Russell H Tobe

Cheryl M Corcoran

Melissa Breland

Anna MacKay-Brandt

Casimir Klim

Stanley J Colcombe

Bennett L Leventhal

Daniel C Javitt

Affiliations

Soon will be listed here.

Abstract

Impairment in social cognition, including emotion recognition, has been extensively studied in both Autism Spectrum Disorders (ASD) and Schizophrenia (SZ). However, the relative patterns of deficit between disorders have been studied to a lesser degree. Here, we applied a social cognition battery incorporating both auditory (AER) and visual (VER) emotion recognition measures to a group of 19 high-functioning individuals with ASD relative to 92 individuals with SZ, and 73 healthy control adult participants. We examined group differences and correlates of basic auditory processing and processing speed. Individuals with SZ were impaired in both AER and VER while ASD individuals were impaired in VER only. In contrast to SZ participants, those with ASD showed intact basic auditory function. Our finding of a dissociation between AER and VER deficits in ASD relative to Sz support modality-specific theories of emotion recognition dysfunction. Future studies should focus on visual system-specific contributions to social cognitive impairment in ASD.

Citing Articles

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References

Rapoport J, Chavez A, Greenstein D, Addington A, Gogtay N . Autism spectrum disorders and childhood-onset schizophrenia: clinical and biological contributions to a relation revisited. J Am Acad Child Adolesc Psychiatry. 2009; 48(1):10-8. PMC: 2664646. DOI: 10.1097/CHI.0b013e31818b1c63. View

Gilman S, Chang J, Xu B, Bawa T, Gogos J, Karayiorgou M . Diverse types of genetic variation converge on functional gene networks involved in schizophrenia. Nat Neurosci. 2012; 15(12):1723-8. PMC: 3689007. DOI: 10.1038/nn.3261. View

Jehna M, Langkammer C, Wallner-Blazek M, Neuper C, Loitfelder M, Ropele S . Cognitively preserved MS patients demonstrate functional differences in processing neutral and emotional faces. Brain Imaging Behav. 2011; 5(4):241-51. DOI: 10.1007/s11682-011-9128-1. View

Gervais H, Belin P, Boddaert N, Leboyer M, Coez A, Sfaello I . Abnormal cortical voice processing in autism. Nat Neurosci. 2004; 7(8):801-2. DOI: 10.1038/nn1291. View

Orbelo D, Grim M, Talbott R, Ross E . Impaired comprehension of affective prosody in elderly subjects is not predicted by age-related hearing loss or age-related cognitive decline. J Geriatr Psychiatry Neurol. 2005; 18(1):25-32. DOI: 10.1177/0891988704272214. View

Mathersul D, McDonald S, Rushby J . Understanding advanced theory of mind and empathy in high-functioning adults with autism spectrum disorder. J Clin Exp Neuropsychol. 2013; 35(6):655-68. DOI: 10.1080/13803395.2013.809700. View

Boucher J, Lewis V, Collis G . Familiar face and voice matching and recognition in children with autism. J Child Psychol Psychiatry. 1998; 39(2):171-81. View

Gur R, Richard J, Hughett P, Calkins M, Macy L, Bilker W . A cognitive neuroscience-based computerized battery for efficient measurement of individual differences: standardization and initial construct validation. J Neurosci Methods. 2009; 187(2):254-62. PMC: 2832711. DOI: 10.1016/j.jneumeth.2009.11.017. View

Baker K, Montgomery A, Abramson R . Brief report: perception and lateralization of spoken emotion by youths with high-functioning forms of autism. J Autism Dev Disord. 2009; 40(1):123-9. DOI: 10.1007/s10803-009-0841-1. View

10.

Eack S, Bahorik A, McKnight S, Hogarty S, Greenwald D, Newhill C . Commonalities in social and non-social cognitive impairments in adults with autism spectrum disorder and schizophrenia. Schizophr Res. 2013; 148(1-3):24-8. PMC: 3732579. DOI: 10.1016/j.schres.2013.05.013. View

11.

Dal Monte O, Krueger F, Solomon J, Schintu S, Knutson K, Strenziok M . A voxel-based lesion study on facial emotion recognition after penetrating brain injury. Soc Cogn Affect Neurosci. 2012; 8(6):632-9. PMC: 3739908. DOI: 10.1093/scan/nss041. View

12.

Bolte S, Poustka F . The recognition of facial affect in autistic and schizophrenic subjects and their first-degree relatives. Psychol Med. 2003; 33(5):907-15. DOI: 10.1017/s0033291703007438. View

13.

Solomon M, Olsen E, Niendam T, Ragland J, Yoon J, Minzenberg M . From lumping to splitting and back again: atypical social and language development in individuals with clinical-high-risk for psychosis, first episode schizophrenia, and autism spectrum disorders. Schizophr Res. 2011; 131(1-3):146-51. PMC: 3143216. DOI: 10.1016/j.schres.2011.03.005. View

14.

Sarkamo T, Tervaniemi M, Soinila S, Autti T, Silvennoinen H, Laine M . Auditory and cognitive deficits associated with acquired amusia after stroke: a magnetoencephalography and neuropsychological follow-up study. PLoS One. 2010; 5(12):e15157. PMC: 2996293. DOI: 10.1371/journal.pone.0015157. View

15.

Greenaway R, Davis G, Plaisted-Grant K . Marked selective impairment in autism on an index of magnocellular function. Neuropsychologia. 2013; 51(4):592-600. DOI: 10.1016/j.neuropsychologia.2013.01.005. View

16.

Juslin P, Laukka P . Communication of emotions in vocal expression and music performance: different channels, same code?. Psychol Bull. 2003; 129(5):770-814. DOI: 10.1037/0033-2909.129.5.770. View

17.

Watkins J, Asarnow R, Tanguay P . Symptom development in childhood onset schizophrenia. J Child Psychol Psychiatry. 1988; 29(6):865-78. DOI: 10.1111/j.1469-7610.1988.tb00759.x. View

18.

Butler P, Abeles I, Weiskopf N, Tambini A, Jalbrzikowski M, Legatt M . Sensory contributions to impaired emotion processing in schizophrenia. Schizophr Bull. 2009; 35(6):1095-107. PMC: 2762631. DOI: 10.1093/schbul/sbp109. View

19.

Harms M, Martin A, Wallace G . Facial emotion recognition in autism spectrum disorders: a review of behavioral and neuroimaging studies. Neuropsychol Rev. 2010; 20(3):290-322. DOI: 10.1007/s11065-010-9138-6. View

20.

Diehl-Schmid J, Pohl C, Ruprecht C, Wagenpfeil S, Foerstl H, Kurz A . The Ekman 60 Faces Test as a diagnostic instrument in frontotemporal dementia. Arch Clin Neuropsychol. 2007; 22(4):459-64. DOI: 10.1016/j.acn.2007.01.024. View