» Articles » PMID: 27081157

PmiRExAt: Plant MiRNA Expression Atlas Database and Web Applications

Overview
Specialty Biology
Date 2016 Apr 16
PMID 27081157
Citations 19
Authors
Affiliations
Soon will be listed here.
Abstract

High-throughput small RNA (sRNA) sequencing technology enables an entirely new perspective for plant microRNA (miRNA) research and has immense potential to unravel regulatory networks. Novel insights gained through data mining in publically available rich resource of sRNA data will help in designing biotechnology-based approaches for crop improvement to enhance plant yield and nutritional value. Bioinformatics resources enabling meta-analysis of miRNA expression across multiple plant species are still evolving. Here, we report PmiRExAt, a new online database resource that caters plant miRNA expression atlas. The web-based repository comprises of miRNA expression profile and query tool for 1859 wheat, 2330 rice and 283 maize miRNA. The database interface offers open and easy access to miRNA expression profile and helps in identifying tissue preferential, differential and constitutively expressing miRNAs. A feature enabling expression study of conserved miRNA across multiple species is also implemented. Custom expression analysis feature enables expression analysis of novel miRNA in total 117 datasets. New sRNA dataset can also be uploaded for analysing miRNA expression profiles for 73 plant species. PmiRExAt application program interface, a simple object access protocol web service allows other programmers to remotely invoke the methods written for doing programmatic search operations on PmiRExAt database.Database URL:http://pmirexat.nabi.res.in.

Citing Articles

Deciphering the impact of microRNAs in plant biology: a review of computational insights and experimental validation.

Palani T, Selvakumar D, Nathan B, Shanmugam V, Duraisamy K, Mannu J Mol Biol Rep. 2025; 52(1):209.

PMID: 39913060 DOI: 10.1007/s11033-025-10273-0.


RiceMetaSys: Drought-miR, a one-stop solution for drought responsive miRNAs-mRNA module in rice.

Kumar D, Venkadesan S, Prabha R, Begam S, Dutta B, Mishra D Database (Oxford). 2024; 2024.

PMID: 39167719 PMC: 11338179. DOI: 10.1093/database/baae076.


Alfin-like (AL) transcription factor family in L.: Genome-wide analysis and expression profiling under different stresses.

Rahman J, Hoque H, Jubayer A, Jewel N, Hasan M, Chowdhury A Biotechnol Rep (Amst). 2024; 43:e00845.

PMID: 38962072 PMC: 11217604. DOI: 10.1016/j.btre.2024.e00845.


Switching action modes of miR408-5p mediates auxin signaling in rice.

Rong F, Lv Y, Deng P, Wu X, Zhang Y, Yue E Nat Commun. 2024; 15(1):2525.

PMID: 38514635 PMC: 10958043. DOI: 10.1038/s41467-024-46765-z.


Identification, characterization of Apyrase (APY) gene family in rice (Oryza sativa) and analysis of the expression pattern under various stress conditions.

Chowdhury A, Hasan M, Bhuiyan F, Islam M, Nayon M, Rahaman M PLoS One. 2023; 18(5):e0273592.

PMID: 37163561 PMC: 10171694. DOI: 10.1371/journal.pone.0273592.


References
1.
Zhai J, Zhao Y, Simon S, Huang S, Petsch K, Arikit S . Plant microRNAs display differential 3' truncation and tailing modifications that are ARGONAUTE1 dependent and conserved across species. Plant Cell. 2013; 25(7):2417-28. PMC: 3753374. DOI: 10.1105/tpc.113.114603. View

2.
Kozomara A, Griffiths-Jones S . miRBase: annotating high confidence microRNAs using deep sequencing data. Nucleic Acids Res. 2013; 42(Database issue):D68-73. PMC: 3965103. DOI: 10.1093/nar/gkt1181. View

3.
Zhang Z, Yu J, Li D, Zhang Z, Liu F, Zhou X . PMRD: plant microRNA database. Nucleic Acids Res. 2009; 38(Database issue):D806-13. PMC: 2808885. DOI: 10.1093/nar/gkp818. View

4.
Rodrigues J, Ruan R, Nishimura T, Sharma M, Sharma R, Ronald P . Imprinted expression of genes and small RNA is associated with localized hypomethylation of the maternal genome in rice endosperm. Proc Natl Acad Sci U S A. 2013; 110(19):7934-9. PMC: 3651473. DOI: 10.1073/pnas.1306164110. View

5.
Tang Z, Zhang L, Xu C, Yuan S, Zhang F, Zheng Y . Uncovering small RNA-mediated responses to cold stress in a wheat thermosensitive genic male-sterile line by deep sequencing. Plant Physiol. 2012; 159(2):721-38. PMC: 3375937. DOI: 10.1104/pp.112.196048. View