Treatment Intensity and Outcome of Nonagenarians Selected for Admission in ICUs: a Multicenter Study of the Outcomerea Research Group

Overview

Journal Ann Intensive Care

Specialty Critical Care

Date 2016 Apr 15

PMID 27076186

Citations 5

Authors

Maite Garrouste-Orgeas

Stephane Ruckly

Charles Gregoire

Anne-Sylvie Dumesnil

Cecile Pommier

Samir Jamali

Dany Golgran-Toledano

Carole Schwebel

Christophe Clech

Lilia Soufir

Muriel Fartoukh

Guillaume Marcotte

Laurent Argaud

Bruno Verdiere

Michael Darmon

Elie Azoulay

Jean-Francois Timsit

Affiliations

Soon will be listed here.

Abstract

Background: Outcome of very elderly patients admitted in intensive care unit (ICU) was most often reported for octogenarians. ICU admission demands for nonagenarians are increasing. The primary objective was to compare outcome and intensity of treatment of octogenarians and nonagenarians.

Methods: We performed an observational study in 12 ICUs of the Outcomerea™ network which prospectively upload data into the Outcomerea™ database. Patients >90 years old (case patients) were matched with patients 80-90 years old (control patients). Matching criteria were severity of illness at admission, center, and year of admission.

Results: A total of 2419 patients aged 80 or older and admitted from September 1997 to September 2013 were included. Among them, 179 (7.9 %) were >90 years old. Matching was performed for 176 nonagenarian patients. Compared with control patients, case patients were more often hospitalized for unscheduled surgery [54 (30.7 %) vs. 42 (23.9 %), p < 0.01] and had less often arterial monitoring for blood pressure [37 (21 %) vs. 53 (30.1 %), p = 0.04] and renal replacement therapy [5 (2.8 %) vs. 14 (8 %), p = 0.05] than control patients. ICU [44 (25 %) vs. 36 (20.5 %), p = 0.28] or hospital mortality [70 (39.8 %) vs. 64 (36.4 %), p = 0.46] and limitation of life-sustaining therapies were not significantly different in case versus control patients, respectively. Only 16/176 (14 %) of case patients were transferred to a geriatric unit.

Conclusion: This multicenter study reported that nonagenarians represented a small fraction of ICU patients. When admitted, these highly selected patients received similar life-sustaining treatments, except RRT, than octogenarians. ICU and hospital mortality were similar between the two groups.

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