Hepatoblastoma: A Need for Cell Lines and Tissue Banks to Develop Targeted Drug Therapies

Overview

Journal Front Pediatr

Specialty Pediatrics

Date 2016 Apr 6

PMID 27047905

Citations 20

Authors

Rishi Raj Rikhi

Kimberlee K Spady

Ruth I Hoffman

Michael S Bateman

Max Bateman

Lisa Easom Howard

Affiliations

Soon will be listed here.

Abstract

Limited research exists regarding the most aggressive forms of hepatoblastoma. Cell lines of the rare subtypes of hepatoblastoma with poor prognosis are not only difficult to attain but also challenging to characterize histologically. A community-driven approach to educating parents and families, regarding the need for donated tissue, is necessary for scientists to have access to resources for murine models and drug discovery. Herein, we describe the currently available resources, existing gaps in research, and the path to move forward for uniform cure of hepatoblastoma.

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