Adult Onset Still's Disease: A Review on Diagnostic Workup and Treatment Options

Overview

Journal Case Rep Rheumatol

Publisher Wiley

Date 2016 Apr 5

PMID 27042373

Citations 20

Authors

Rajesh Gopalarathinam

Eric Orlowsky

Ramesh Kesavalu

Sreeteja Yelaminchili

Affiliations

Soon will be listed here.

Abstract

Adult onset Still's disease (AOSD) is a rare systemic inflammatory disease of unknown etiology and pathogenesis that presents in 5 to 10% of patients as fever of unknown origin (FUO) accompanied by systemic manifestations. We report an interesting case of a 33-year-old African-American male who presented with one-month duration of FUO along with skin rash, sore throat, and arthralgia. After extensive workup, potential differential diagnoses were ruled out and the patient was diagnosed with AOSD based on the Yamaguchi criteria. The case history, incidence, pathogenesis, clinical manifestations, differential diagnoses, diagnostic workup, treatment modalities, and prognosis of AOSD are discussed in this case report.

Citing Articles

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Differential diagnostic performance of PET/CT in adult-onset still's disease and lymphoma: a retrospective pilot study.

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Adult-Onset Still's Disease-A Complex Disease, a Challenging Treatment.

Macovei L, Burlui A, Bratoiu I, Rezus C, Cardoneanu A, Richter P Int J Mol Sci. 2022; 23(21).

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