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A Cohort Study of the Acute and Chronic Respiratory Effects of Toner Exposure Among Handlers: a Longitudinal Analyses from 2004 to 2013

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Journal Ind Health
Date 2016 Mar 30
PMID 27021062
Citations 2
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Abstract

This study examines the acute and chronic respiratory effects of toner exposure based on markers for interstitial pneumonia, oxidative stress and pulmonary function tests. A total of 112 subjects working in a Japanese toner and photocopier manufacturing company participated in this study in 2004. We annually conducted personal exposure measurements, pulmonary function tests, chest X-ray examinations, biomarkers, and questionnaires on respiratory symptoms to the subjects. We report in this paper the results of the analysis of combined annual survey point data from 2004 to 2008 and data from three annual survey points, 2004, 2008, and 2013. During these survey periods, we observed that none of subjects had a new onset of respiratory disease or died of such a disease. In both the analyses, there were no significant differences in each biomarker and pulmonary function tests within the subjects, nor between a toner-handling group and a non-toner-handling group, except for a few results on pulmonary function tests. The findings of this study suggest that there were no acute and chronic respiratory effects of toner exposure in this cohort group, although the number of subjects was small and the level of toner exposure in this worksite was low.

Citing Articles

Effects of toner-handling work on respiratory function, chest X-ray findings, and biomarkers of inflammation, allergy, and oxidative stress: a 10-year prospective Japanese cohort study.

Terunuma N, Ikegami K, Kitamura H, Ando H, Kurosaki S, Masuda M BMC Pulm Med. 2020; 20(1):280.

PMID: 33109132 PMC: 7590607. DOI: 10.1186/s12890-020-01320-6.


Assessing the chronic respiratory health risk associated with inhalation exposure to powdered toner for printing in actual working conditions: a cohort study on occupationally exposed workers over 10 years.

Nakadate T, Yamano Y, Yamauchi T, Okubo S, Nagashima D BMJ Open. 2018; 8(10):e022049.

PMID: 30341118 PMC: 6196812. DOI: 10.1136/bmjopen-2018-022049.

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