Are Self-stigma, Quality of Life, and Clinical Data Interrelated in Schizophrenia Spectrum Patients? A Cross-sectional Outpatient Study

Overview

Journal Patient Prefer Adherence

Date 2016 Mar 29

PMID 27019596

Citations 10

Authors

Michaela Holubova

Jan Prasko

Klara Latalova

Marie Ociskova

Ales Grambal

Dana Kamaradova

Kristyna Vrbova

Radovan Hruby

Affiliations

Soon will be listed here.

Abstract

Background: Current research attention has been moving toward the needs of patients and their consequences for the quality of life (QoL). Self-stigma is a maladaptive psychosocial phenomenon disturbing the QoL in a substantial number of psychiatric patients. In our study, we examined the relationship between demographic data, the severity of symptoms, self-stigma, and QoL in patients with schizophrenia spectrum disorder.

Methods: Probands who met International Classification of Diseases-10 criteria for schizophrenia spectrum disorder (schizophrenia, schizoaffective disorder, or delusional disorder) were recruited in the study. We studied the correlations between the QoL measured by the QoL Satisfaction and Enjoyment Questionnaire, self-stigma assessed by the Internalized Stigma of Mental Illness, and severity of the disorder measured by the objective and subjective Clinical Global Impression severity scales in this cross-sectional study.

Results: A total of 109 psychotic patients and 91 healthy controls participated in the study. Compared with the control group, there was a lower QoL and a higher score of self-stigmatization in psychotic patients. We found the correlation between an overall rating of self-stigmatization, duration of disorder, and QoL. The level of self-stigmatization correlated positively with total symptom severity score and negatively with the QoL. Multiple regression analysis revealed that the overall rating of objective symptom severity and the score of self-stigma were significantly associated with the QoL.

Conclusion: Our study suggests a negative impact of self-stigma level on the QoL in patients suffering from schizophrenia spectrum disorders.

Citing Articles

Rasch Modeling and Differential Item Functioning of the Self-Stigma Scale-Short Version among People with Three Different Psychiatric Disorders.

Fan C, Chang K, Lee K, Yang W, Pakpour A, Potenza M Int J Environ Res Public Health. 2022; 19(14).

PMID: 35886695 PMC: 9317808. DOI: 10.3390/ijerph19148843.

Prevalence and factors associated with higher levels of perceived stigma among people with schizophrenia Addis Ababa, Ethiopia.

Tesfaw G, Kibru B, Ayano G Int J Ment Health Syst. 2020; 14:19.

PMID: 32190107 PMC: 7071705. DOI: 10.1186/s13033-020-00348-9.

Positive Coping and Resilience as Mediators Between Negative Symptoms and Disability Among Patients With Schizophrenia.

Chen H, Xu J, Mao Y, Sun L, Sun Y, Zhou Y Front Psychiatry. 2019; 10:641.

PMID: 31551832 PMC: 6748026. DOI: 10.3389/fpsyt.2019.00641.

Internalized stigma and its correlates among patients with severe mental illness.

Szczesniak D, Kobylko A, Wojciechowska I, Klapcinski M, Rymaszewska J Neuropsychiatr Dis Treat. 2018; 14:2599-2608.

PMID: 30349258 PMC: 6183546. DOI: 10.2147/NDT.S169051.

Quality of life, self-stigma, and hope in schizophrenia spectrum disorders: a cross-sectional study.

Vrbova K, Prasko J, Ociskova M, Kamaradova D, Marackova M, Holubova M Neuropsychiatr Dis Treat. 2017; 13:567-576.

PMID: 28260904 PMC: 5328600. DOI: 10.2147/NDT.S122483.

References

Adewuya A, Owoeye A, Erinfolami A, Ola B . Correlates of self-stigma among outpatients with mental illness in Lagos, Nigeria. Int J Soc Psychiatry. 2010; 57(4):418-27. DOI: 10.1177/0020764010363522. View

Awad A, Voruganti L . Impact of atypical antipsychotics on quality of life in patients with schizophrenia. CNS Drugs. 2004; 18(13):877-93. DOI: 10.2165/00023210-200418130-00004. View

Latalova K, Prasko J, Diveky T, Kamaradova D, Velartova H . Quality of life in patients with bipolar disorder--a comparison with schizophrenic patients and healthy controls. Psychiatr Danub. 2011; 23(1):21-6. View

Schulze B, Angermeyer M . Subjective experiences of stigma. A focus group study of schizophrenic patients, their relatives and mental health professionals. Soc Sci Med. 2002; 56(2):299-312. DOI: 10.1016/s0277-9536(02)00028-x. View

Gerlinger G, Hauser M, De Hert M, Lacluyse K, Wampers M, Correll C . Personal stigma in schizophrenia spectrum disorders: a systematic review of prevalence rates, correlates, impact and interventions. World Psychiatry. 2013; 12(2):155-64. PMC: 3683268. DOI: 10.1002/wps.20040. View

Boyer L, Baumstarck K, Boucekine M, Blanc J, Lancon C, Auquier P . Measuring quality of life in patients with schizophrenia:an overview. Expert Rev Pharmacoecon Outcomes Res. 2013; 13(3):343-9. DOI: 10.1586/erp.13.15. View

Tang I, Wu H . Quality of life and self-stigma in individuals with schizophrenia. Psychiatr Q. 2012; 83(4):497-507. DOI: 10.1007/s11126-012-9218-2. View

Sidlova M, Prasko J, Jelenova D, Kovacsova A, Latalova K, Sigmundova Z . The quality of life of patients suffering from schizophrenia--a comparison with healthy controls. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2011; 155(2):173-80. DOI: 10.5507/bp.2011.010. View

Awad A, Voruganti L . Measuring quality of life in patients with schizophrenia: an update. Pharmacoeconomics. 2012; 30(3):183-95. DOI: 10.2165/11594470-000000000-00000. View

10.

Herrman H, Hawthorne G, Thomas R . Quality of life assessment in people living with psychosis. Soc Psychiatry Psychiatr Epidemiol. 2002; 37(11):510-8. DOI: 10.1007/s00127-002-0587-y. View

11.

Tsang H, Fung K, Chung R . Self-stigma and stages of change as predictors of treatment adherence of individuals with schizophrenia. Psychiatry Res. 2010; 180(1):10-5. DOI: 10.1016/j.psychres.2009.09.001. View

12.

Wegener S, Redoblado-Hodge M, Lucas S, Fitzgerald D, Harris A, Brennan J . Relative contributions of psychiatric symptoms and neuropsychological functioning to quality of life in first-episode psychosis. Aust N Z J Psychiatry. 2005; 39(6):487-92. DOI: 10.1080/j.1440-1614.2005.01608.x. View

13.

Karagianis J, Novick D, Pecenak J, Haro J, Dossenbach M, Treuer T . Worldwide-Schizophrenia Outpatient Health Outcomes (W-SOHO): baseline characteristics of pan-regional observational data from more than 17,000 patients. Int J Clin Pract. 2009; 63(11):1578-88. DOI: 10.1111/j.1742-1241.2009.02191.x. View

14.

Ritsner M, Ben-Avi I, Ponizovsky A, Timinsky I, Bistrov E, Modai I . Quality of life and coping with schizophrenia symptoms. Qual Life Res. 2003; 12(1):1-9. DOI: 10.1023/a:1022049111822. View

15.

Vrbova K, Kamaradova D, Latalova K, Ociskova M, Prasko J, Mainerova B . Self-stigma and adherence to medication in patients with psychotic disorders--cross-sectional study. Neuro Endocrinol Lett. 2015; 35(7):645-52. View

16.

Lehman A . The effects of psychiatric symptoms on quality of life assessments among the chronic mentally ill. Eval Program Plann. 1982; 6(2):143-51. DOI: 10.1016/0149-7189(83)90028-9. View

17.

Skantze K, Malm U, Dencker S, MAY P, Corrigan P . Comparison of quality of life with standard of living in schizophrenic out-patients. Br J Psychiatry. 1992; 161:797-801. DOI: 10.1192/bjp.161.6.797. View

18.

Remberk B, Hintze B, Rybakowski F . Executive functioning improves after remission of psychosis and may not deteriorate at short follow-up in early-onset schizophrenia. Neuro Endocrinol Lett. 2015; 36(2):153-60. View

19.

Browne S, Roe M, Lane A, Gervin M, Morris M, Kinsella A . Quality of life in schizophrenia: relationship to sociodemographic factors, symptomatology and tardive dyskinesia. Acta Psychiatr Scand. 1996; 94(2):118-24. DOI: 10.1111/j.1600-0447.1996.tb09835.x. View

20.

Marwaha S, Johnson S . Schizophrenia and employment - a review. Soc Psychiatry Psychiatr Epidemiol. 2004; 39(5):337-49. DOI: 10.1007/s00127-004-0762-4. View