The Clinical Utility of the Foveal Electroretinogram: a Review
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The historical development of the foveal electroretinogram is reviewed. The factors required to obtain a local cone electroretinogram with a small focal source of illumination against a lighted background are discussed. From these considerations and various studies of macular degeneration, the optimal size of the foveal source is found to be 5 degrees diameter or less. Applications of the foveal electroretinogram in various diseases are summarized. The foveal electroretinogram is abnormal with reduced acuity in age-related macular degeneration, juvenile macular degeneration (Stargardt's disease), retinitis pigmentosa, and diabetic retinopathy. Normal foveal electroretinograms are found in optic atrophy, amblyopia, and optic neuritis. Foveal electroretinograms are normal or abnormal in Best's disease, central serous retinopathy, and several other diseases discussed.
Toward a clinical optoretinogram: a review of noninvasive, optical tests of retinal neural function.
Jonnal R Ann Transl Med. 2021; 9(15):1270.
PMID: 34532407 PMC: 8421939. DOI: 10.21037/atm-20-6440.
Role of Electrophysiology in the Early Diagnosis and Follow-Up of Diabetic Retinopathy.
Pescosolido N, Barbato A, Stefanucci A, Buomprisco G J Diabetes Res. 2015; 2015:319692.
PMID: 26075282 PMC: 4436463. DOI: 10.1155/2015/319692.
Evaluation of the LKC stimulator for focal ERG testing.
Lyons J, Sapper D Doc Ophthalmol. 2001; 103(2):163-73.
PMID: 11720257 DOI: 10.1023/a:1012421111342.
Precision LED-based stimulator for focal electroretinography.
Fadda A, Falsini B Med Biol Eng Comput. 1997; 35(4):441-4.
PMID: 9327628 DOI: 10.1007/BF02534106.
Porciatti V, Moretti G, Ciavarella P, Falsini B Doc Ophthalmol. 1993; 84(1):39-46.
PMID: 8223109 DOI: 10.1007/BF01203281.