Dynamic Reorganization of the Actin Cytoskeleton

Overview

Journal F1000Res

Specialties Biomedical Engineering
Science

Date 2016 Mar 19

PMID 26989473

Citations 16

Authors

Gaelle Letort

Hajer Ennomani

Laurene Gressin

Manuel Thery

Laurent Blanchoin

Affiliations

Soon will be listed here.

Abstract

Cellular processes, including morphogenesis, polarization, and motility, rely on a variety of actin-based structures. Although the biochemical composition and filament organization of these structures are different, they often emerge from a common origin. This is possible because the actin structures are highly dynamic. Indeed, they assemble, grow, and disassemble in a time scale of a second to a minute. Therefore, the reorganization of a given actin structure can promote the formation of another. Here, we discuss such transitions and illustrate them with computer simulations.

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