» Articles » PMID: 26985281

Giant Cell Reparative Granuloma of the Hallux Following Enchondroma

Overview
Journal Pan Afr Med J
Date 2016 Mar 18
PMID 26985281
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

Giant cell reparative granuloma (GCRG) is a rare, benign intra osseous lytic lesion occurring especially in gnathis bone but also seen in feet and hands. It has similar clinical and radiological presentations than giant cell tumor, chondroblastoma, aneurysmal bone cyst, and hyperparathyroidism brown tumors but with specific histological findings We report a case of a GCRG of hallux phalanx in 18 years old patient appearing many years after enchondroma curettage and grafting. Radiographs showed a multiloculated osteolytic lesions involving whole phalanx with cortical thinning and without fluid-fluid levels in CT view. Expected to be an enchondroma recurrence, second biopsy confirmed diagnosis of GCRG with specific histological findings. Although if aetiopathogeny remains unknown, GCRG is reported to be a local non neoplasic reaction to an intraosseous hemorrhage. Our exceptional case claims that this tumor can appear in reaction to cellular disturbance primary or secondary.

Citing Articles

Three-dimensional printed talar prosthesis with biological function for giant cell tumor of the talus: A case report and review of the literature.

Yang Q, Mu M, Tao X, Tang K World J Clin Cases. 2021; 9(13):3147-3156.

PMID: 33969102 PMC: 8080752. DOI: 10.12998/wjcc.v9.i13.3147.


Denosumab Treatment for Aggressive Multiple Recurrent Familial Central Giant-cell Granulomas.

Rytkonen E, Ottavainen V, Rytkonen A, Uusitalo S, Lehenkari P, K Sandor G Ann Maxillofac Surg. 2019; 8(2):265-269.

PMID: 30693243 PMC: 6327812. DOI: 10.4103/ams.ams_192_18.


Giant cell reparative granuloma of the scapula: report of a case and literature review.

Angelini A, Pagliarini E, Belluzzi E, Cappellesso R, Ruggieri P Skeletal Radiol. 2019; 48(8):1293-1298.

PMID: 30607456 DOI: 10.1007/s00256-018-3132-0.

References
1.
Ilaslan H, Sundaram M, Unni K . Solid variant of aneurysmal bone cysts in long tubular bones: giant cell reparative granuloma. AJR Am J Roentgenol. 2003; 180(6):1681-7. DOI: 10.2214/ajr.180.6.1801681. View

2.
Subasi M, Kapukaya A, Buyukbayram H, Bukte Y . Giant-cell reparative granuloma of the tibia. Acta Orthop Belg. 2003; 69(4):363-7. View

3.
Gouin F, Grimaud E, Redini F, Moreau A, Passuti N, Heymann D . Metatarsal giant cell tumors and giant cell reparative granuloma are similar entities. Clin Orthop Relat Res. 2003; (416):278-84. DOI: 10.1097/01.blo.0000093016.90435.f6. View

4.
Lorenzo J, Dorfman H . Giant-cell reparative granuloma of short tubular bones of the hands and feet. Am J Surg Pathol. 1980; 4(6):551-63. DOI: 10.1097/00000478-198012000-00006. View

5.
Picci P, Baldini N, Sudanese A, Boriani S, Campanacci M . Giant cell reparative granuloma and other giant cell lesions of the bones of the hands and feet. Skeletal Radiol. 1986; 15(6):415-21. DOI: 10.1007/BF00355097. View