Assessment of the Cardiac Autonomic Nervous System in Mercury-Exposed Individuals Via Post-Exercise Heart Rate Recovery

Overview

Journal Med Princ Pract

Publisher Karger

Specialties General Medicine
Medical Education

Date 2016 Mar 11

PMID 26964065

Citations 3

Authors

Omer Hinc Yilmaz

Ugur Nadir Karakulak

Engin Tutkun

Ceylan Bal

Meside Gunduzoz

Emine Ercan Onay

Mehmet Ayturk

Mujgan Tek Ozturk

Mehmet Erdem Alaguney

Affiliations

Soon will be listed here.

Abstract

Objective: The aim of this study was to assess exercise heart rate recovery (HRR) indices in mercury-exposed individuals when evaluating their cardiac autonomic function.

Subjects And Methods: Twenty-eight mercury-exposed individuals and 28 healthy controls were enrolled. All the subjects underwent exercise testing and transthoracic echocardiography. The HRR indices were calculated by subtracting the first- (HRR1), second- (HRR2) and third-minute (HRR3) heart rates from the maximal heart rate. The two groups were evaluated in terms of exercise test parameters, especially HRR, and a correlation analysis was performed between blood, 24-hour urine and hair mercury levels and the test parameters.

Results: The mercury-exposed and control groups were similar in age (37.2 ± 6.6 vs. 36.9 ± 9.0 years), had an identical gender distribution (16 females and 12 males) and similar left ventricular ejection fractions (65.5 ± 3.1 vs. 65.4 ± 3.1%). The mean HRR1 [25.6 ± 6.5 vs. 30.3 ± 8.2 beats per min (bpm); p = 0.009], HRR2 (43.5 ± 5.3 vs. 47.8 ± 5.5 bpm; p = 0.010) and HRR3 (56.8 ± 5.1 vs. 59.4 ± 6.3 bpm; p = 0.016) values were significantly lower in the mercury-exposed group than in the healthy controls. However, there were no significant correlations between blood, urine and hair mercury levels and exercise test parameters.

Conclusions: Mercury-exposed individuals had lower HRR indices than normal subjects. In these individuals, mercury exposure measurements did not show correlations with the exercise test parameters, but age did show a negative correlation with these parameters. Therefore, cardiac autonomic functions might be involved in cases of mercury exposure.

Citing Articles

Blood lead and mercury levels are associated with low resting heart rate in community adolescent boys.

Liu J, Portnoy J, Um P, Cui N, Rudo-Hutt A, Yan C Int J Hyg Environ Health. 2021; 233:113685.

PMID: 33556713 PMC: 7965295. DOI: 10.1016/j.ijheh.2020.113685.

Heart Rate Variability, Heart Rate Recovery, and Heart Rate Turbulence Represent Different Components of the Cardiac Autonomic Nervous System.

Gulgun M Med Princ Pract. 2016; 26(1):98-99.

PMID: 27728910 PMC: 5588333. DOI: 10.1159/000452335.

Attenuated Heart Rate Recovery in Mercury-Exposed Individuals.

Tekin A Med Princ Pract. 2016; 26(1):94-95.

PMID: 27710959 PMC: 5588328. DOI: 10.1159/000452247.

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