NGF FLIPs TrkA Onto the Death TRAIL in Neuroblastoma Cells

Overview

Journal Cell Death Dis

Specialties Cell Biology
General Medicine

Date 2016 Mar 11

PMID 26962689

Citations 4

Authors

P Ruggeri

L Cappabianca

A R Farina

L Gneo

A R Mackay

Affiliations

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Citing Articles

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Gene expression and molecular pathway activation signatures of -amplified neuroblastomas.

Petrov I, Suntsova M, Ilnitskaya E, Roumiantsev S, Sorokin M, Garazha A Oncotarget. 2017; 8(48):83768-83780.

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Epileptic Encephalopathy Caused by Mutations in the Guanine Nucleotide Exchange Factor DENND5A.

Han C, Alkhater R, Froukh T, Minassian A, Galati M, Liu R Am J Hum Genet. 2016; 99(6):1359-1367.

PMID: 27866705 PMC: 5142110. DOI: 10.1016/j.ajhg.2016.10.006.

TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic "Achilles heel" for the TrkAIII oncoprotein in neuroblastoma.

Gneo L, Ruggeri P, Cappabianca L, Farina A, Di Ianni N, Mackay A Oncotarget. 2016; 7(49):80820-80841.

PMID: 27821809 PMC: 5348358. DOI: 10.18632/oncotarget.13098.

Nerve growth factor: role in growth, differentiation and controlling cancer cell development.

Aloe L, Rocco M, Balzamino B, Micera A J Exp Clin Cancer Res. 2016; 35(1):116.

PMID: 27439311 PMC: 4955168. DOI: 10.1186/s13046-016-0395-y.

References

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Ruggeri P, Cappabianca L, Farina A, Gneo L, Mackay A . NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis. Cell Death Discov. 2016; 2:16004. PMC: 4979468. DOI: 10.1038/cddiscovery.2016.4. View

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