Stereotactic Body Radiotherapy for the Treatment of Renal Tumors
Overview
Authors
Affiliations
The purpose of this study was to evaluate the response of actively growing renal masses to stereotactic body radiation therapy (SBRT). We retrospectively reviewed our institutional review board-approved kidney database and identified 4 patients who underwent SBRT, 15 Gy dose, for their rapidly growing renal masses. Three patients had a decreased tumor size after radiation treatment by 20.8%, 38.1%, and 20%. The other patient had a size gain of 5.6%. This patient maintained a similar tumor growth rate before and after SBRT. Mean follow-up time was 13.8 months. SBRT represents an effective management option in select patients with larger rapidly growing kidney masses.
de Angelis M, Morra S, Scheipner L, Siech C, Jannello L, Baudo A World J Urol. 2024; 42(1):193.
PMID: 38530480 DOI: 10.1007/s00345-024-04856-y.
Radiation induces dynamic changes to the T cell repertoire in renal cell carcinoma patients.
Chow J, Hoffend N, Abrams S, Schwaab T, Singh A, Muhitch J Proc Natl Acad Sci U S A. 2020; 117(38):23721-23729.
PMID: 32900949 PMC: 7519245. DOI: 10.1073/pnas.2001933117.
Ng S, Ning M, Lee P, McMahon R, Siva S, Chuong M Adv Radiat Oncol. 2020; 5(4):761-773.
PMID: 32775790 PMC: 7406732. DOI: 10.1016/j.adro.2020.06.011.
Singh A, Winslow T, Kermany M, Goritz V, Heit L, Miller A Clin Cancer Res. 2017; 23(17):5055-5065.
PMID: 28630212 PMC: 5581708. DOI: 10.1158/1078-0432.CCR-16-2946.