Difficulties in the Diagnosis and Management of Alveolar Hydatid Disease: A Case Series

Overview

Journal Caspian J Intern Med

Specialty General Medicine

Date 2016 Mar 10

PMID 26958334

Citations 7

Authors

Ghodratollah Maddah

Abbas Abdollahi

Reza Sharifi-Nooghabi

Alireza Tavassoli

Mohammad Taghi Rajabi-Mashadi

Azadeh Jabbari-Nooghabi

Mehdi Jabbari-Nooghabi

Affiliations

Soon will be listed here.

Abstract

Background: Alveolar echinococcosis (AE) is a chronic, rare and sometimes lethal parasitic infection in humans, caused by the larval stage of the fox tapeworm Echinococcus multilocularis. This study aimed to investigate the clinical aspects and treatment outcomes of patients with alveolar hydatid disease.

Methods: The medical records of patients with alveolar echinococcosis admitted between 1997 and 2012 were reviewed. Diagnosis was confirmed by physical examination, ultrasonography and CT scanning and MRI. Various treatment techniques were used such as complete liver resection in seven (38.89%) patients, biliary bypass in two (11.11%) patients, laparotomy and tumor biopsy in eight (44.44%) patients and long term medical treatment in one (5.56%) patient. After discharge, all patients were followed to determine the effect of treatment, complications, recurrences and survival.

Results: A total of 18 patients with mean age of 46.11±15.14 years (range 23-74 years) were studied. The disease was more prevalent in women than men (78.9% vs 4, 21.1%, P=0.021). Fourteen (77.78%) patients live in Chenaran, a town located in Khorasan, Iran). Death occurred in (22.22%) patients after an average period of 45.70±7.50 months after disease onset. 14 remaining patients survived after a mean follow-up duration of 54.60±29.17 months.

Conclusion: Diagnosis of alveolar echinococcosis should be considered in endemic area. Early diagnosis and treatment is associated with excellent outcome.

Citing Articles

Epidemiology of echinococcosis in Iran: a systematic review and meta-analysis.

Mahmoudi S, Mamishi S, Banar M, Pourakbari B, Keshavarz H BMC Infect Dis. 2019; 19(1):929.

PMID: 31684882 PMC: 6830007. DOI: 10.1186/s12879-019-4458-5.

A multiplex PCR for differential detection of Echinococcus granulosus sensu stricto, Echinococcus multilocularis and Echinococcus canadensis in China.

Shang J, Zhang G, Liao S, Huang Y, Yu W, He W Infect Dis Poverty. 2019; 8(1):68.

PMID: 31362789 PMC: 6668063. DOI: 10.1186/s40249-019-0580-2.

Worldwide literature on epidemiology of human alveolar echinococcosis: a systematic review of research published in the twenty-first century.

Baumann S, Shi R, Liu W, Bao H, Schmidberger J, Kratzer W Infection. 2019; 47(5):703-727.

PMID: 31147846 PMC: 8505309. DOI: 10.1007/s15010-019-01325-2.

Case Report: Role of Interventional Radiology in the Management of Patients with Alveolar Echinococcus: Successful Management of Three Cases.

Dagoglu-Kartal M, Ciftci T, Ozer C, Akinci D, Akhan O Am J Trop Med Hyg. 2018; 98(5):1403-1407.

PMID: 29611496 PMC: 5953349. DOI: 10.4269/ajtmh.17-0089.

Lasiopodomys fuscus as an important intermediate host for Echinococcus multilocularis: isolation and phylogenetic identification of the parasite.

Cai Q, Han X, Yang Y, Zhang X, Ma L, Karanis P Infect Dis Poverty. 2018; 7(1):27.

PMID: 29602313 PMC: 5878421. DOI: 10.1186/s40249-018-0409-4.

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