Bilateral Primary Mucinous Carcinoma of the Eyelid

Overview

Journal Ophthalmic Plast Reconstr Surg

Specialties General Surgery
Ophthalmology

Date 2016 Mar 8

PMID 26950474

Citations 3

Authors

Christopher K H Burris

Meisha L Raven

Maria E Rodriguez

Heather D Potter

Mark J Lucarelli

Daniel M Albert

Affiliations

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Abstract

The aim of this study is to report a case of bilateral primary mucinous carcinoma of the eyelids. This is a case report and literature review. A 71-year-old female presented with primary mucinous carcinoma of the left upper eyelid, which was excised with Mohs surgery. One year later, she developed primary mucinous carcinoma of the right upper eyelid, which was also treated Mohs surgery. Extensive workup was negative for evidence of an unknown primary carcinoma or metastasis. Primary mucinous carcinoma of the eyelids may occur as multifocal tumors, and bilateral disease is not necessarily indicative of metastatic disease.

Citing Articles

A Rare Case of Primary Adenocarcinoma of the Eyelid: Case Presentation and Review of Literature.

Soror N, Lutaya I, Shah P, Hemrock L, Bennett R, Gibson G Cureus. 2021; 13(7):e16580.

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Multifocal primary mucinous carcinoma of the eyelids: Implications for management.

Stiegler J, Mogan S, Pukhalskaya T, Verhave B, Ibrahim S JAAD Case Rep. 2021; 9:78-80.

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Primary Mucinous Adenocarcinoma of the Upper Eyelid in an African American Female: A Rare Clinical Entity. A Case Report and Literature Review.

Ashok Kumar P, Paulraj S, Hahn S, Sivapiragasam A Cureus. 2020; 11(11):e6254.

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References

Miyasaka M, Tanaka R, Hirabayashi K, Yamazaki A, Shinohara H, Taira H . Primary mucinous carcinoma of the skin: a case of metastasis after 10 years of disease-free interval. Eur J Plast Surg. 2010; 32(4):189-193. PMC: 2837212. DOI: 10.1007/s00238-008-0304-5. View

Ivan D, Nash J, Prieto V, Calonje E, Lyle S, Diwan A . Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin. J Cutan Pathol. 2007; 34(6):474-80. DOI: 10.1111/j.1600-0560.2006.00644.x. View

Marra D, Schanbacher C, Torres A . Mohs micrographic surgery of primary cutaneous mucinous carcinoma using immunohistochemistry for margin control. Dermatol Surg. 2004; 30(5):799-802. DOI: 10.1111/j.1524-4725.2004.30223.x. View

Papalas J, Proia A . Primary mucinous carcinoma of the eyelid: a clinicopathologic and immunohistochemical study of 4 cases and an update on recurrence rates. Arch Ophthalmol. 2010; 128(9):1160-5. DOI: 10.1001/archophthalmol.2010.177. View

Brownstein M, HELWIG E . Metastatic tumors of the skin. Cancer. 1972; 29(5):1298-307. DOI: 10.1002/1097-0142(197205)29:5<1298::aid-cncr2820290526>3.0.co;2-6. View

Sanke R . Primary mucinous adenocarcinoma of the eyelid. Ophthalmic Surg. 1989; 20(9):668-71. View

Snow S, Reizner G . Mucinous eccrine carcinoma of the eyelid. Cancer. 1992; 70(8):2099-104. DOI: 10.1002/1097-0142(19921015)70:8<2099::aid-cncr2820700815>3.0.co;2-c. View

HEADINGTON J . Primary mucinous carcinoma of skin: histochemistry and electron microscopy. Cancer. 1977; 39(3):1055-63. DOI: 10.1002/1097-0142(197703)39:3<1055::aid-cncr2820390308>3.0.co;2-g. View

Kazakov D, Suster S, LeBoit P, Calonje E, Bisceglia M, Kutzner H . Mucinous carcinoma of the skin, primary, and secondary: a clinicopathologic study of 63 cases with emphasis on the morphologic spectrum of primary cutaneous forms: homologies with mucinous lesions in the breast. Am J Surg Pathol. 2005; 29(6):764-82. DOI: 10.1097/01.pas.0000159104.02985.6b. View

10.

Breiting L, Dahlstrom K, Christensen L, Winther J, Breiting V . Primary mucinous carcinoma of the skin. Am J Dermatopathol. 2007; 29(6):595-6. DOI: 10.1097/DAD.0b013e318158d878. View

11.

Bertagnoli R, Cook D, GOLDMAN G . Bilateral primary mucinous carcinoma of the eyelid treated with Mohs surgery. Dermatol Surg. 1999; 25(7):566-8. DOI: 10.1046/j.1524-4725.1999.99070.x. View

12.

Shockman S, Krug L, Lountzis N . Remission of metastatic primary mucinous carcinoma of the skin with anastrozole. J Am Acad Dermatol. 2014; 71(1):e27-8. DOI: 10.1016/j.jaad.2013.12.032. View

13.

Wright J, Font R . Mucinous sweat gland adenocarcinoma of eyelid: a clinicopathologic study of 21 cases with histochemical and electron microscopic observations. Cancer. 1979; 44(5):1757-68. DOI: 10.1002/1097-0142(197911)44:5<1757::aid-cncr2820440533>3.0.co;2-8. View

14.

Burris C, Anand Rajan K, Iliff N . Primary mucinous carcinoma of the periocular region: successful management with local resections over 30 years. BMJ Case Rep. 2013; 2013. PMC: 3603836. DOI: 10.1136/bcr-2012-007972. View