Alpha 2.0
Login Register
» Articles » PMID: 26940015

FOXO3a & Haematopoietic Stem Cells: Goodbye PI3K, Hello SIRT1?

Overview
Journal Cell Cycle
Specialty Cell Biology
Date 2016 Mar 5
PMID 26940015
Citations 1
Authors
Evan E Santo
Jihye Paik
Affiliations
Soon will be listed here.
Citing Articles

FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage.

Bigarella C, Li J, Rimmele P, Liang R, Sobol R, Ghaffari S J Biol Chem. 2016; 292(7):3005-3015.

PMID: 27994057 PMC: 5314194. DOI: 10.1074/jbc.M116.769455.

References
1.
Li X, Li J, Wilson A, Sipple J, Schick J, Pang Q . Fancd2 is required for nuclear retention of Foxo3a in hematopoietic stem cell maintenance. J Biol Chem. 2014; 290(5):2715-27. PMC: 4317007. DOI: 10.1074/jbc.M114.619536. View
2.
Matsuzaki H, Ichino A, Hayashi T, Yamamoto T, Kikkawa U . Regulation of intracellular localization and transcriptional activity of FOXO4 by protein kinase B through phosphorylation at the motif sites conserved among the FOXO family. J Biochem. 2005; 138(4):485-91. DOI: 10.1093/jb/mvi146. View
3.
Mihaylova M, Vasquez D, Ravnskjaer K, Denechaud P, Yu R, Alvarez J . Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell. 2011; 145(4):607-21. PMC: 3117637. DOI: 10.1016/j.cell.2011.03.043. View
4.
Yamagata K, Daitoku H, Takahashi Y, Namiki K, Hisatake K, Kako K . Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt. Mol Cell. 2008; 32(2):221-31. DOI: 10.1016/j.molcel.2008.09.013. View
5.
Chen C, Liu Y, Liu R, Ikenoue T, Guan K, Liu Y . TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J Exp Med. 2008; 205(10):2397-408. PMC: 2556783. DOI: 10.1084/jem.20081297. View