A Clinical Study to Compare Between Resting and Stimulated Whole Salivary Flow Rate and PH Before and After Complete Denture Placement in Different Age Groups

Overview

Journal J Indian Prosthodont Soc

Specialty Dentistry

Date 2016 Mar 2

PMID 26929540

Citations 11

Authors

B C Muddugangadhar

Rajashekar Sangur

I V Rudraprasad

D B Nandeeshwar

B H Dhanya Kumar

Affiliations

Soon will be listed here.

Abstract

Purpose: This study compared the flow rate and pH of resting (unstimulated) and stimulated whole saliva before and after complete denture placement in different age groups.

Materials And Methods: Fifty healthy, non-medicated edentulous individuals of different age groups requiring complete denture prostheses were selected from the outpatient department. The resting (unstimulated) and stimulated whole saliva and pH were measured at three stages i.e., i)Before complete denture placement;ii)Immediately after complete denture placement; andiii)After 2 to 3 months of complete denture placement. Saliva production was stimulated by chewing paraffin wax. pH was determined by using a digital pH meter.

Results: Statistically significant differences were seen in resting(unstimulated) and stimulated whole salivary flow rate and pH obtained before, immediately after, and after 2 to 3 months of complete denture placement. No statistically significant differences were found between the different age groups in resting (unstimulated) as well as stimulated whole salivary flow rate and pH.

Conclusion: Stimulated whole salivary flow rates and pH were significantly higher than resting (unstimulated) whole salivary flow rates and pH obtained before, immediately after, and after 2 to 3 months of complete denture placement. No age related variations in whole salivary flow rate and pH were observed in healthy, non-medicated individuals.

Clinical Implications: The assessment of salivary flow rate, pH in different age groups is of prognostic value, which is an important aspect to be considered in the practice of removable prosthodontics.

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References

Enberg N, Alho H, Loimaranta V, Lenander-Lumikari M . Saliva flow rate, amylase activity, and protein and electrolyte concentrations in saliva after acute alcohol consumption. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001; 92(3):292-8. DOI: 10.1067/moe.2001.116814. View

Dodds M, Johnson D, Yeh C . Health benefits of saliva: a review. J Dent. 2005; 33(3):223-33. DOI: 10.1016/j.jdent.2004.10.009. View

Edgerton M, Tabak L, LeVine M . Saliva: a significant factor in removable prosthodontic treatment. J Prosthet Dent. 1987; 57(1):57-66. DOI: 10.1016/0022-3913(87)90117-x. View

Pedersen A, Bardow A, Beier Jensen S, Nauntofte B . Saliva and gastrointestinal functions of taste, mastication, swallowing and digestion. Oral Dis. 2002; 8(3):117-29. DOI: 10.1034/j.1601-0825.2002.02851.x. View

Streckfus C, Bigler L . Saliva as a diagnostic fluid. Oral Dis. 2002; 8(2):69-76. DOI: 10.1034/j.1601-0825.2002.1o834.x. View

MANDEL I . The functions of saliva. J Dent Res. 1987; 66 Spec No:623-7. DOI: 10.1177/00220345870660S203. View

MANDEL I . The diagnostic uses of saliva. J Oral Pathol Med. 1990; 19(3):119-25. DOI: 10.1111/j.1600-0714.1990.tb00809.x. View

Gandara B, Izutsu K, Truelove E, MANDEL I, Sommers E, Ensign W . Sialochemistry of whole, parotid, and labial minor gland saliva in patients with oral lichen planus. J Dent Res. 1987; 66(11):1619-22. DOI: 10.1177/00220345870660110201. View

Niedermeier W, Kramer R . Salivary secretion and denture retention. J Prosthet Dent. 1992; 67(2):211-6. DOI: 10.1016/0022-3913(92)90455-j. View

10.

Lamkin M, Oppenheim F . Structural features of salivary function. Crit Rev Oral Biol Med. 1993; 4(3-4):251-9. DOI: 10.1177/10454411930040030101. View

11.

Kaufman E, Lamster I . The diagnostic applications of saliva--a review. Crit Rev Oral Biol Med. 2002; 13(2):197-212. DOI: 10.1177/154411130201300209. View

12.

MANDEL I . Relation of saliva and plaque to caries. J Dent Res. 1974; 53(2):246-66. DOI: 10.1177/00220345740530021201. View

13.

Percival R, Challacombe S, Marsh P . Flow rates of resting whole and stimulated parotid saliva in relation to age and gender. J Dent Res. 1994; 73(8):1416-20. DOI: 10.1177/00220345940730080401. View

14.

Techanitiswad T, Rahemtulla F, McMillan T, Bradley E, Wahlin Y . Analyses of salivary components in leukemia patients receiving chemotherapy. Oral Surg Oral Med Oral Pathol. 1992; 73(1):35-46. DOI: 10.1016/0030-4220(92)90151-f. View

15.

Shern R, Fox P, Cain J, Li S . A method for measuring the flow of saliva from the minor salivary glands. J Dent Res. 1990; 69(5):1146-9. DOI: 10.1177/00220345900690050501. View

16.

SREEBNY L . Saliva in health and disease: an appraisal and update. Int Dent J. 2000; 50(3):140-61. DOI: 10.1111/j.1875-595x.2000.tb00554.x. View

17.

Jensen J, Karatsaidis A, Brodin P . Salivary secretion: stimulatory effects of chewing-gum versus paraffin tablets. Eur J Oral Sci. 1998; 106(4):892-6. DOI: 10.1046/j.0909-8836..t01-7-.x. View

18.

Tylenda C, Ship J, Fox P, Baum B . Evaluation of submandibular salivary flow rate in different age groups. J Dent Res. 1988; 67(9):1225-8. DOI: 10.1177/00220345880670091501. View

19.

PARVINEN T, Larmas M . The relation of stimulated salivary flow rate and pH to Lactobacillus and yeast concentrations in saliva. J Dent Res. 1981; 60(12):1929-35. DOI: 10.1177/00220345810600120201. View

20.

Atkinson J, Grisius M, Massey W . Salivary hypofunction and xerostomia: diagnosis and treatment. Dent Clin North Am. 2005; 49(2):309-26. DOI: 10.1016/j.cden.2004.10.002. View