Description of Three Novel Lagenidium (Oomycota) Species Causing Infection in Mammals

Overview

Journal Rev Iberoam Micol

Specialty Microbiology

Date 2016 Mar 1

PMID 26924580

Citations 4

Authors

Leonel Mendoza

John W Taylor

Edward D Walker

Raquel Vilela

Affiliations

Soon will be listed here.

Abstract

Background: Recent molecular phylogenetic analysis of Lagenidium strains recovered from subcutaneous lesions in cats, dogs, and a human with lagenidiosis resolved into four clades; one of them was Lagenidium giganteum, but three others were novel.

Aims: Due to the recent increase in L. giganteum infections from mammals, we studied 21 Lagenidium strains isolated from dogs and a human available in our collection.

Methods: Molecular phylogenetic studies and phenotypic characteristics were used to characterize the strains.

Results: We report the finding of three novel species, herein designated as Lagenidium ajelloi, sp. nov., Lagenidium albertoi sp. nov, and Lagenidium vilelae sp. nov. Their morphological and growth features are also presented.

Conclusions: Our study revealed the presence of three novel Lagenidium species infecting mammals.

Citing Articles

Metagenomic identification of a novel oomycete cultured from a pyogranulomatous mass on the tail of a domestic cat.

Bowman J, Gull T, Ulmanis E, Ogunbadewa A, Shen Z, Johnson G J Vet Diagn Invest. 2023; 35(5):507-513.

PMID: 37317863 PMC: 10467462. DOI: 10.1177/10406387231180310.

High-Throughput Sequencing of Environmental DNA as a Tool for Monitoring Eukaryotic Communities and Potential Pathogens in a Coastal Upwelling Ecosystem.

Rios-Castro R, Romero A, Aranguren R, Pallavicini A, Banchi E, Novoa B Front Vet Sci. 2021; 8:765606.

PMID: 34805343 PMC: 8595318. DOI: 10.3389/fvets.2021.765606.

., a cultivable holocarpic parasitoid of the early-diverging .

Buaya A, Thines M Fungal Syst Evol. 2020; 6:129-137.

PMID: 32904153 PMC: 7451777. DOI: 10.3114/fuse.2020.06.07.

Oomycete metabarcoding reveals the presence of spp. in phytotelmata.

Leoro-Garzon P, Gonedes A, Olivera I, Tartar A PeerJ. 2019; 7:e7903.

PMID: 31632856 PMC: 6796956. DOI: 10.7717/peerj.7903.

References

Reinprayoon U, Permpalung N, Kasetsuwan N, Plongla R, Mendoza L, Chindamporn A . Lagenidium sp. ocular infection mimicking ocular pythiosis. J Clin Microbiol. 2013; 51(8):2778-80. PMC: 3719631. DOI: 10.1128/JCM.00783-13. View

Quiroz Velasquez P, Abiff S, Fins K, Conway Q, Salazar N, Delgado A . Transcriptome analysis of the entomopathogenic oomycete Lagenidium giganteum reveals putative virulence factors. Appl Environ Microbiol. 2014; 80(20):6427-36. PMC: 4178636. DOI: 10.1128/AEM.02060-14. View

Gaastra W, Lipman L, de Cock A, Exel T, Pegge R, Scheurwater J . Pythium insidiosum: an overview. Vet Microbiol. 2010; 146(1-2):1-16. DOI: 10.1016/j.vetmic.2010.07.019. View

Barron G . Nematophagous fungi: new species of the Lagenidiales endoparasitic on Rhabditis. Antonie Van Leeuwenhoek. 1976; 42(1-2):131-9. DOI: 10.1007/BF00399457. View

Grooters A, Hodgin E, Bauer R, Detrisac C, Znajda N, Thomas R . Clinicopathologic findings associated with Lagenidium sp. infection in 6 dogs: initial description of an emerging oomycosis. J Vet Intern Med. 2003; 17(5):637-46. DOI: 10.1111/j.1939-1676.2003.tb02494.x. View

Jiang R, Tyler B . Mechanisms and evolution of virulence in oomycetes. Annu Rev Phytopathol. 2012; 50:295-318. DOI: 10.1146/annurev-phyto-081211-172912. View

Soanes D, Richards T . Horizontal gene transfer in eukaryotic plant pathogens. Annu Rev Phytopathol. 2014; 52:583-614. DOI: 10.1146/annurev-phyto-102313-050127. View

Beakes G, Glockling S, Sekimoto S . The evolutionary phylogeny of the oomycete "fungi". Protoplasma. 2011; 249(1):3-19. DOI: 10.1007/s00709-011-0269-2. View

Grooters A . Pythiosis, lagenidiosis, and zygomycosis in small animals. Vet Clin North Am Small Anim Pract. 2003; 33(4):695-720, v. DOI: 10.1016/s0195-5616(03)00034-2. View

10.

ROGERS-TALBERT R . The fungus Lagenidium callinectes Couch (1942) on eggs of the blue crab in Chesapeake Bay. Biol Bull. 1948; 95(2):214-28. View

11.

de Cock A, Mendoza L, Padhye A, Ajello L, Kaufman L . Pythium insidiosum sp. nov., the etiologic agent of pythiosis. J Clin Microbiol. 1987; 25(2):344-9. PMC: 265897. DOI: 10.1128/jcm.25.2.344-349.1987. View

12.

Vilela R, Taylor J, Walker E, Mendoza L . Lagenidium giganteum pathogenicity in mammals. Emerg Infect Dis. 2015; 21(2):290-7. PMC: 4313650. DOI: 10.3201/eid2102.141091. View

13.

Seidl M, Van den Ackerveken G, Govers F, Snel B . Reconstruction of oomycete genome evolution identifies differences in evolutionary trajectories leading to present-day large gene families. Genome Biol Evol. 2012; 4(3):199-211. PMC: 3318443. DOI: 10.1093/gbe/evs003. View

14.

Levesque C, de Cock A . Molecular phylogeny and taxonomy of the genus Pythium. Mycol Res. 2005; 108(Pt 12):1363-83. DOI: 10.1017/s0953756204001431. View

15.

Mendoza L, Prendas J . A method to obtain rapid zoosporogenesis of Pythium insidiosum. Mycopathologia. 1988; 104(1):59-62. DOI: 10.1007/BF00437925. View

16.

Schurko A, Mendoza L, Levesque C, Desaulniers N, de Cock A, Klassen G . A molecular phylogeny of Pythium insidiosum. Mycol Res. 2003; 107(Pt 5):537-44. DOI: 10.1017/s0953756203007718. View