Type D Personality Predicts Poor Medication Adherence in Chinese Patients with Type 2 Diabetes Mellitus: A Six-Month Follow-Up Study

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2016 Feb 20

PMID 26894925

Citations 20

Authors

Xuemei Li

Shengfa Zhang

Huiwen Xu

Xinfeng Tang

Huixuan Zhou

Jiaqi Yuan

Xiaohua Wang

Zhiyong Qu

Fugang Wang

He Zhu

Shuai Guo

Donghua Tian

Weijun Zhang

Affiliations

Soon will be listed here.

Abstract

Background: Type D personality and medication nonadherence have been shown to be associated with poor health outcomes. Type D personality is associated with poor medication adherence in patients with coronary artery disease, myocardial infarction, and heart failure. However, the relationship between type D personality and medication adherence in patients with Type 2 Diabetes Mellitus (T2DM) remains unknown. This study aims to examine whether type D personality was associated with medication adherence in patients with T2DM.

Design And Settings: A follow-up study was conducted in general hospital of the People's Liberation Army in Beijing.

Methods: 412 T2DM patients (205 females), who were recruited by circular systematic random sampling, provided demographic and baseline data about medical information and completed measures of Type D personality. Then, 330 patients went on to complete a self-report measure of medication adherence at the sixth month after baseline data collection. Chi-square test, t tests, and hierarchical multiple regression analyses were conducted, as needed.

Results: Patients with type D personality were significantly more likely to have poor medication adherence (p<0.001). Type D personality predicts poor medication adherence before and after controlling for covariates when it was analyzed as a categorical variable. However, the dimensional construct of type D personality was not associated with medication adherence when analyzed as a continuous variable.

Conclusion: Although, as a dimensional construct, type D personality may not reflect the components of the personality associated with poor medication adherence in patients with T2DM, screening for type D personality may help to identify those who are at higher risk of poor medication adherence. Interventions, aiming to improve medication adherence, should be launched for these high-risk patients.

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References

Odegard P, Capoccia K . Medication taking and diabetes: a systematic review of the literature. Diabetes Educ. 2007; 33(6):1014-29. DOI: 10.1177/0145721707308407. View

Ferguson E, Williams L, OConnor R, Howard S, Hughes B, Johnston D . A taxometric analysis of type-D personality. Psychosom Med. 2009; 71(9):981-6. DOI: 10.1097/PSY.0b013e3181bd888b. View

Lee G, Wang H, Liu K, Cheung Y, Morisky D, Wong M . Determinants of medication adherence to antihypertensive medications among a Chinese population using Morisky Medication Adherence Scale. PLoS One. 2013; 8(4):e62775. PMC: 3636185. DOI: 10.1371/journal.pone.0062775. View

Williams L, OConnor R, Grubb N, OCarroll R . Type D personality and three-month psychosocial outcomes among patients post-myocardial infarction. J Psychosom Res. 2012; 72(6):422-6. DOI: 10.1016/j.jpsychores.2012.02.007. View

Denollet J . DS14: standard assessment of negative affectivity, social inhibition, and Type D personality. Psychosom Med. 2005; 67(1):89-97. DOI: 10.1097/01.psy.0000149256.81953.49. View

Schiffer A, Smith O, Pedersen S, Widdershoven J, Denollet J . Type D personality and cardiac mortality in patients with chronic heart failure. Int J Cardiol. 2009; 142(3):230-5. DOI: 10.1016/j.ijcard.2008.12.090. View

Dieltjens M, Vanderveken O, Van den Bosch D, Wouters K, Denollet J, Verbraecken J . Impact of type D personality on adherence to oral appliance therapy for sleep-disordered breathing. Sleep Breath. 2012; 17(3):985-91. DOI: 10.1007/s11325-012-0788-x. View

Bauer A, Schillinger D, Parker M, Katon W, Adler N, Adams A . Health literacy and antidepressant medication adherence among adults with diabetes: the diabetes study of Northern California (DISTANCE). J Gen Intern Med. 2013; 28(9):1181-7. PMC: 3744297. DOI: 10.1007/s11606-013-2402-8. View

Cohen H, Shmukler C, Ullman R, Rivera C, Walker E . Measurements of medication adherence in diabetic patients with poorly controlled HbA(1c). Diabet Med. 2010; 27(2):210-6. PMC: 4626013. DOI: 10.1111/j.1464-5491.2009.02898.x. View

10.

Wong M, Wu C, Wang H, Li H, Hui E, Lam A . Association between the 8-item Morisky medication adherence scale (MMAS-8) score and glycaemic control among Chinese diabetes patients. J Clin Pharmacol. 2014; 55(3):279-87. DOI: 10.1002/jcph.408. View

11.

Denollet J, Conraads V, Brutsaert D, De Clerck L, Stevens W, Vrints C . Cytokines and immune activation in systolic heart failure: the role of Type D personality. Brain Behav Immun. 2003; 17(4):304-9. DOI: 10.1016/s0889-1591(03)00060-6. View

12.

Walker R, Smalls B, Hernandez-Tejada M, Campbell J, Davis K, Egede L . Effect of diabetes fatalism on medication adherence and self-care behaviors in adults with diabetes. Gen Hosp Psychiatry. 2012; 34(6):598-603. PMC: 3479321. DOI: 10.1016/j.genhosppsych.2012.07.005. View

13.

Coyne J, Jaarsma T, Luttik M, van Sonderen E, Van Veldhuisen D, Sanderman R . Lack of prognostic value of type D personality for mortality in a large sample of heart failure patients. Psychosom Med. 2011; 73(7):557-62. DOI: 10.1097/PSY.0b013e318227ac75. View

14.

Aquarius A, Smolderen K, Hamming J, de Vries J, Vriens P, Denollet J . Type D personality and mortality in peripheral arterial disease: a pilot study. Arch Surg. 2009; 144(8):728-33. DOI: 10.1001/archsurg.2009.75. View

15.

Buysman E, Liu F, Hammer M, Langer J . Impact of medication adherence and persistence on clinical and economic outcomes in patients with type 2 diabetes treated with liraglutide: a retrospective cohort study. Adv Ther. 2015; 32(4):341-55. PMC: 4415988. DOI: 10.1007/s12325-015-0199-z. View

16.

Lane J, McCaskill C, Williams P, Parekh P, Feinglos M, Surwit R . Personality correlates of glycemic control in type 2 diabetes. Diabetes Care. 2000; 23(9):1321-5. DOI: 10.2337/diacare.23.9.1321. View

17.

Clifford S, Perez-Nieves M, Skalicky A, Reaney M, Coyne K . A systematic literature review of methodologies used to assess medication adherence in patients with diabetes. Curr Med Res Opin. 2014; 30(6):1071-85. DOI: 10.1185/03007995.2014.884491. View

18.

Odegard P, Gray S . Barriers to medication adherence in poorly controlled diabetes mellitus. Diabetes Educ. 2008; 34(4):692-7. DOI: 10.1177/0145721708320558. View

19.

Molloy G, Perkins-Porras L, Strike P, Steptoe A . Type-D personality and cortisol in survivors of acute coronary syndrome. Psychosom Med. 2008; 70(8):863-8. DOI: 10.1097/PSY.0b013e3181842e0c. View

20.

Tzeng J, Chang C, Chang H, Lin C . Assessing analgesic regimen adherence with the Morisky Medication Adherence Measure for Taiwanese patients with cancer pain. J Pain Symptom Manage. 2008; 36(2):157-66. DOI: 10.1016/j.jpainsymman.2007.10.015. View