» Articles » PMID: 26857237

Long-term Antihypertensive Effects of Far-infrared Ray Irradiated from Wooden Board in Spontaneously Hypertensive Rats

Overview
Publisher Biomed Central
Date 2016 Feb 10
PMID 26857237
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Far-infrared ray (FIR) has been widely used in promoting health and has been shown to exert beneficial effects in vascular function. The non-thermal effect of FIR has been found to play a significant role in the protective effect on some vascular-related diseases, but its protective effects and use against hypertension have not been clearly presented.

Methods: In the present study, by using a wooden board coated with FIR-irradiated materials, we evaluated the long-term antihypertensive effect on spontaneously hypertensive rats (SHRs) in the environment in contact with the FIR-irradiated wooden board. SHRs were placed on the wooden board with or without FIR radiation for 4 weeks.

Results: The systolic blood pressure (BP) of SHRs undergoing different treatments was measured weekly using a tail-cuff method. FIR radiation significantly reduced the systolic BP of the SHRs along with a decreasing plasma level of angiotensin II and an increasing plasma level of bradykinin. In addition, long-term contact of FIR did not significantly affect the BP in normotensive Wistar Kyoto rats (WKYs).

Conclusions: Our results provided the evidence based on which FIR radiation could be considered an effective non-pharmacological choice for preventing hypertension.

Citing Articles

Far-Infrared-Emitting Sericite Board Upregulates Endothelial Nitric Oxide Synthase Activity through Increasing Biosynthesis of Tetrahydrobiopterin in Endothelial Cells.

Kim S, Lee I, Song H, Choi S, Nagar H, Kim S Evid Based Complement Alternat Med. 2019; 2019:1813282.

PMID: 31781259 PMC: 6875339. DOI: 10.1155/2019/1813282.

References
1.
Meigs J, Hu F, Rifai N, Manson J . Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus. JAMA. 2004; 291(16):1978-86. DOI: 10.1001/jama.291.16.1978. View

2.
Zhang M, Wang G, Wang A, Tong W, Zhang Y . Association of hypertension with coexistence of abnormal metabolism and inflammation and endothelial dysfunction. Blood Press. 2012; 22(3):151-7. DOI: 10.3109/08037051.2012.745226. View

3.
Sato J, Kinugasa M, Satomi-Kobayashi S, Hatakeyama K, Knox A, Asada Y . Family with sequence similarity 5, member C (FAM5C) increases leukocyte adhesion molecules in vascular endothelial cells: implication in vascular inflammation. PLoS One. 2014; 9(9):e107236. PMC: 4175995. DOI: 10.1371/journal.pone.0107236. View

4.
Bakris G . Are there effects of renin-angiotensin system antagonists beyond blood pressure control?. Am J Cardiol. 2010; 105(1 Suppl):21A-9A. DOI: 10.1016/j.amjcard.2009.10.010. View

5.
Unger T, Stoppelhaar M . Rationale for double renin-angiotensin-aldosterone system blockade. Am J Cardiol. 2007; 100(3A):25J-31J. DOI: 10.1016/j.amjcard.2007.05.011. View