» Articles » PMID: 26854172

Role of Hybrid Brain Imaging in Neuropsychiatric Disorders

Overview
Specialty Radiology
Date 2016 Feb 9
PMID 26854172
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

This is a focused review of imaging literature to scope the utility of hybrid brain imaging in neuropsychiatric disorders. The review focuses on brain imaging modalities that utilize hybrid (fusion) techniques to characterize abnormal brain molecular signals in combination with structural and functional changes that have been observed in neuropsychiatric disorders. An overview of clinical hybrid brain imaging technologies for human use is followed by a selective review of the literature that conceptualizes the use of these technologies in understanding basic mechanisms of major neuropsychiatric disorders and their therapeutics. Neuronal network abnormalities are highlighted throughout this review to scope the utility of hybrid imaging as a potential biomarker for each disorder.

Citing Articles

Altered Language-Related Effective Connectivity in Patients with Benign Childhood Epilepsy with Centrotemporal Spikes.

Yang F, Tan J, Huang Y, Xiao R, Wang X, Han Y Life (Basel). 2023; 13(2).

PMID: 36836947 PMC: 9960797. DOI: 10.3390/life13020590.


Multi-modal intermediate integrative methods in neuropsychiatric disorders: A review.

Wang Y, Tang S, Ma R, Zamit I, Wei Y, Pan Y Comput Struct Biotechnol J. 2022; 20:6149-6162.

PMID: 36420153 PMC: 9674886. DOI: 10.1016/j.csbj.2022.11.008.


Editorial: Emotional Disturbance and Brain Imaging in Neuropsychiatric Disorders.

Esposito R, Zhang F, Hu M, Li P, Guo W Front Psychiatry. 2021; 12:632244.

PMID: 33815169 PMC: 8009964. DOI: 10.3389/fpsyt.2021.632244.


Rationale, Relevance, and Limits of Stress-Induced Psychopathology in Rodents as Models for Psychiatry Research: An Introductory Overview.

Italia M, Forastieri C, Longaretti A, Battaglioli E, Rusconi F Int J Mol Sci. 2020; 21(20).

PMID: 33050350 PMC: 7589795. DOI: 10.3390/ijms21207455.

References
1.
Mulders P, van Eijndhoven P, Schene A, Beckmann C, Tendolkar I . Resting-state functional connectivity in major depressive disorder: A review. Neurosci Biobehav Rev. 2015; 56:330-44. DOI: 10.1016/j.neubiorev.2015.07.014. View

2.
Logothetis N, Pfeuffer J . On the nature of the BOLD fMRI contrast mechanism. Magn Reson Imaging. 2005; 22(10):1517-31. DOI: 10.1016/j.mri.2004.10.018. View

3.
Posner J, Hellerstein D, Gat I, Mechling A, Klahr K, Wang Z . Antidepressants normalize the default mode network in patients with dysthymia. JAMA Psychiatry. 2013; 70(4):373-82. PMC: 3935731. DOI: 10.1001/jamapsychiatry.2013.455. View

4.
Rowe C, Ackerman U, Browne W, Mulligan R, Pike K, OKeefe G . Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism. Lancet Neurol. 2008; 7(2):129-35. DOI: 10.1016/S1474-4422(08)70001-2. View

5.
Pichler B, Judenhofer M, Pfannenberg C . Multimodal imaging approaches: PET/CT and PET/MRI. Handb Exp Pharmacol. 2008; (185 Pt 1):109-32. DOI: 10.1007/978-3-540-72718-7_6. View