Drug Eluting Biliary Stents to Decrease Stent Failure Rates: A Review of the Literature

Overview

Journal World J Gastrointest Endosc

Publisher Baishideng Publishing Group

Date 2016 Feb 4

PMID 26839648

Citations 13

Authors

Joseph Shatzel

Jisoo Kim

Kartik Sampath

Sharjeel Syed

Jennifer Saad

Zilla H Hussain

Kabir Mody

J Marc Pipas

Stuart Gordon

Timothy Gardner

Richard I Rothstein

Affiliations

Soon will be listed here.

Abstract

Biliary stenting is clinically effective in relieving both malignant and non-malignant obstructions. However, there are high failure rates associated with tumor ingrowth and epithelial overgrowth as well as internally from biofilm development and subsequent clogging. Within the last decade, the use of prophylactic drug eluting stents as a means to reduce stent failure has been investigated. In this review we provide an overview of the current research on drug eluting biliary stents. While there is limited human trial data regarding the clinical benefit of drug eluting biliary stents in preventing stent obstruction, recent research suggests promise regarding their safety and potential efficacy.

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