Zinc-modified Nanopolymers Improve the Quality of Resin-dentin Bonded Interfaces

Overview

Journal Clin Oral Investig

Specialty Dentistry

Date 2016 Feb 3

PMID 26832781

Citations 10

Authors

Raquel Osorio

Inmaculada Cabello

Antonio L Medina-Castillo

Estrella Osorio

Manuel Toledano

Affiliations

Soon will be listed here.

Abstract

Introduction: Demineralized collagen fibers at the hybrid layer are susceptible to degradation. Remineralization may aid to improve bond longevity.

Objectives: The aim of the present study was to infiltrate zinc and calcium-loaded polymeric nanoparticles into demineralized dentin to facilitate hybrid layer remineralization.

Materials And Methods: Zinc or calcium-loaded polymeric nanoparticles were infiltrated into etched dentin, and Single Bond Adhesive was applied. Bond strength was tested after 24 h and 6 months storage. Nanomechanical properties, dye-assisted confocal laser microscopy, and Masson's trichrome staining evaluation were performed to assess for the hybrid layer morphology, permeability, and remineralization ability after 24 h and 3 months. Data were analyzed by ANOVA and Student-Newman-Keuls multiple comparisons tests (p < 0.05).

Results: Immediate bond strength was not affected by nanoparticles infiltration (25 to 30 MPa), while after 6 months, bond strengths were maintained (22 to 24 MPa). After 3 months, permeability occurred only in specimens in which nanoparticles were not infiltrated. Dentin remineralization, at the bottom of the hybrid layer, was observed in all groups. After microscopy analysis, zinc-loaded nanoparticles were shown to facilitate calcium deposition throughout the entire hybrid layer. Young's modulus at the hybrid layer increased from 2.09 to 3.25 GPa after 3 months, in specimens with zinc nanoparticles; meanwhile, these values were reduced from 1.66 to 0.49 GPa, in the control group.

Conclusion: Infiltration of polymeric nanoparticles into demineralized dentin increased long-term bond strengths. Zinc-loaded nanoparticles facilitate dentin remineralization within the complete resin-dentin interface.

Clinical Relevance: Resin-dentin bond longevity and dentin remineralization at the hybrid layer were facilitated by zinc-loaded nanoparticles.

Citing Articles

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Unraveling Nanomaterials in Biomimetic Mineralization of Dental Hard Tissue: Focusing on Advantages, Mechanisms, and Prospects.

Dai D, Li D, Zhang C Adv Sci (Weinh). 2024; 11(40):e2405763.

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The influence of neutral MDP-Na salt on dentin bond performance and remineralization potential of etch-&-rinse adhesive.

Li M, Zheng H, Xu Y, Qiu Y, Wang Y, Jin X BMC Oral Health. 2024; 24(1):997.

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Ingles M, Vasconcelos E Cruz J, Mano Azul A, Polido M, Delgado A Polymers (Basel). 2022; 14(19).

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Effect of Collagen Crosslinkers on Dentin Bond Strength of Adhesive Systems: A Systematic Review and Meta-Analysis.

Hardan L, Daood U, Bourgi R, Cuevas-Suarez C, Devoto W, Zarow M Cells. 2022; 11(15).

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