Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora Cassiicola

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2016 Feb 2

PMID 26828473

Citations 5

Authors

Dong-Lin Zhao

Chang-Lun Shao

Chao-Yi Wang

Mei Wang

Lu-Jia Yang

Chang-Yun Wang

Affiliations

Soon will be listed here.

Abstract

Two new naphthalenones, corynenones A and B (1 and 2), and one new depsidone, corynesidone E (3), together with one known depsidone, corynesidone A (4) and two known diphenyl ethers, corynethers A (5) and B (6), were isolated from the sponge-derived fungus Corynespora cassiicola XS-20090I7. Their structures including absolute configurations were determined by spectroscopic data and electronic circular dichroism (ECD) spectra. Compounds 4 and 5 showed cytotoxicity against human promyelocytic leukemia HL-60 and human cervical carcinoma HeLa cell lines.

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