Plasma Calprotectin Level: Usage in Distinction of Uncomplicated from Complicated Acute Appendicitis

Overview

Journal World J Emerg Surg

Publisher Biomed Central

Specialty General Surgery

Date 2016 Jan 29

PMID 26819626

Citations 6

Authors

Murat Cikot

Kivanc Derya Peker

Mehmet Abdussamet Bozkurt

Ali Kocatas

Osman Kones

Sinan Binboga

Asuman Gedikbasi

Halil Alis

Affiliations

Soon will be listed here.

Abstract

Background: The aim of this study was to identify the diagnostic role of plasma calprotectin value for a distinction of presence acute appendicitis and the indifference of uncomplicated from complicated acute appendicitis.

Methods: Plasma calprotectin, white blood cell and C-reactive protein values of 89 patients, who have undergone laparoscopic appendectomy between January 2013 and May 2013 were evaluated.

Results: Calprotectin was 91 ng/mL (range 45-538) for acute appendicitis and 47 ng/ml (range 28-205) for the control group. There was a positive, statistically significant relation between calprotectin and C-reactive protein values (r = 0. 292 p = 0. 001, respectively). There was no statistically significant difference was determined between calprotectin and white blood cell values (r = 0. 142 p = 0. 187, respectively). CRP and Cal values were significantly higher in patients with a complicated AA group than in those with uncomplicated AA (p = 0. 014, p = 0. 0001, respectively) whereas white blood cell counts did not differ significantly between two groups (p = 0. 164).

Conclusion: Plasma calprotectin levels were increased in patients with acute appendicitis and should use in a distinction of uncomplicated from complicated acute appendicitis patients.

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