Myocardial Recovery During Mechanical Circulatory Support: Long-term Outcome and Elective Ventricular Assist Device Implantation to Promote Recovery As a Treatment Goal

Overview

Journal Heart Lung Vessel

Specialty Anesthesiology

Date 2016 Jan 27

PMID 26811834

Citations 16

Authors

Michael Dandel

Roland Hetzer

Affiliations

Soon will be listed here.

Abstract

Even after incomplete myocardial recovery during mechanical circulatory support, long-term survival rates after ventricular assist device (VAD) explantation can be better than those expected after heart transplantation even for patients with chronic non-ischemic cardiomyopathy as the underlying cause for VAD implantation. The elective therapeutic use of ventricular assist devices for heart failure reversal in its early stage is a future goal. It may be possible to achieve it by developing tools to predict heart failure reversibility even before ventricular assist device implantation and increasing the number of weaning candidates by improvement of adjunctive therapies to optimize unloading-promoted recovery. Special attention is focused on the long-term stability of cardiac remission after VAD removal, the clinical relevance unloading-promoted myocardial recovery and on the current knowledge about a potential prediction of myocardial recovery during long-term VAD support already before VAD implantation.

Citing Articles

Role of Echocardiography in the Management of Patients with Advanced (Stage D) Heart Failure Related to Nonischemic Cardiomyopathy.

Dandel M Rev Cardiovasc Med. 2024; 23(6):214.

PMID: 39077176 PMC: 11273760. DOI: 10.31083/j.rcm2306214.

Predictors of long-term success after successful explantation of continuous flow left ventricular assist device support.

Gyoten T, Amiya E, Saito A, Ono M Interdiscip Cardiovasc Thorac Surg. 2024; 38(6).

PMID: 38830049 PMC: 11878525. DOI: 10.1093/icvts/ivae091.

Cardiological Challenges Related to Long-Term Mechanical Circulatory Support for Advanced Heart Failure in Patients with Chronic Non-Ischemic Cardiomyopathy.

Dandel M J Clin Med. 2023; 12(20).

PMID: 37892589 PMC: 10607800. DOI: 10.3390/jcm12206451.

Myocardial Recovery.

Chrysakis N, Xanthopoulos A, Magouliotis D, Starling R, Drakos S, Triposkiadis F Diagnostics (Basel). 2023; 13(8).

PMID: 37189604 PMC: 10138096. DOI: 10.3390/diagnostics13081504.

Patient-tailored silicone plug for HeartMate 3™ left ventricular assist device explantation.

Elbayomi M, Tandler R, Ebel N, Schubert D, Werner S, Kondruweit M J Artif Organs. 2023; 27(2):159-161.

PMID: 37099051 PMC: 11126425. DOI: 10.1007/s10047-023-01397-w.

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