» Articles » PMID: 26798441

Long-term Outcomes After Stenting As a "bridge to Surgery" for the Management of Acute Obstruction Secondary to Colorectal Cancer

Overview
Date 2016 Jan 23
PMID 26798441
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

Obstructive symptoms are present in 8% of cases at the time of initial diagnosis in cases of colorectal cancer. Emergency surgery has been classically considered the treatment of choice in these patients. However, in the majority of studies, emergency colorectal surgery is burdened with higher morbidity and mortality rates than elective surgery, and many patients require temporal colostomy which deteriorates their quality of life and becomes permanent in 10%-40% of cases. The aim of stenting by-pass to surgery is to transform emergency surgery into elective surgery in order to improve surgical results, obtain an accurate tumoral staging and detection of synchronous lesions, stabilization of comorbidities and performance of laparoscopic surgery. Immediate results were more favourable in patients who were stented concerning primary anastomosis, permanent stoma, wound infection and overall morbidity, having the higher surgical risk patients the greater benefit. However, some findings laid out the possible implication of stenting in long-term results of oncologic treatment. Perforation after stenting is related to tumoral recurrence. In studies with perforation rates above 8%, higher recurrences rates in young patients and lower disease free survival have been shown. On the other hand, after stenting the number of removed lymph nodes in the surgical specimen is larger, patients can receive adjuvant chemotherapy earlier and in a greater percentage and the number of patients who can be surgically treated with laparoscopic surgery is larger. Finally, there are no consistent studies able to demonstrate that one strategy is superior to the other in terms of oncologic benefits. At present, it would seem wise to assume a higher initial complication rate in young patients without relevant comorbidities and to accept the risk of local recurrence in old patients (> 70 years) or with high surgical risk (ASA III/IV).

Citing Articles

Safety evaluation of preoperative stent insertion and clinical analysis on comparison of outcomes between preoperative stent insertion and emergency surgery in the treatment of obstructive left-sided colorectal cancer.

Han L, Song X, Yu B, Zhou M, Zhang L, Sun G Pak J Med Sci. 2020; 36(3):376-381.

PMID: 32292437 PMC: 7150377. DOI: 10.12669/pjms.36.3.1707.


Better recurrence-free survival after stent bridge to surgery compared to emergency surgery for obstructive left-sided colonic cancer in patients with stage III status of the American Joint Committee on Cancer (AJCC): a bicentric retrospective study.

Lara-Romero C, Vilches A, Caunedo-Alvarez A, Hergueta-Delgado P, Lavin-Castejon I, Andrade-Bellido R Int J Colorectal Dis. 2019; 34(7):1241-1250.

PMID: 31129696 DOI: 10.1007/s00384-019-03318-x.


Do Self-Expanding Metal Stents as a Bridge to Surgery Benefit All Patients with Obstructive Left-Side Colorectal Cancers?.

Zhang J, Hou P, Liao T, Wei Y, Chen X, Lin B Gastroenterol Res Pract. 2019; 2019:7418348.

PMID: 30863441 PMC: 6377959. DOI: 10.1155/2019/7418348.


Long-term oncologic outcomes of stent as a bridge to surgery versus emergency surgery in malignant left side colonic obstructions: a meta-analysis.

Ceresoli M, Allievi N, Coccolini F, Montori G, Fugazzola P, Pisano M J Gastrointest Oncol. 2017; 8(5):867-876.

PMID: 29184691 PMC: 5674262. DOI: 10.21037/jgo.2017.09.04.

References
1.
Pessione S, Petruzzelli L, Gentilli S, Mioli P . [Treatment of neoplastic stenosis of the left colon: presurgical expandable metal stent vs emergency surgery. Comparison of results and survival rates]. Chir Ital. 2007; 59(5):661-9. View

2.
Kim J, Hur H, Min B, Sohn S, Cho C, Kim N . Oncologic outcomes of self-expanding metallic stent insertion as a bridge to surgery in the management of left-sided colon cancer obstruction: comparison with nonobstructing elective surgery. World J Surg. 2009; 33(6):1281-6. DOI: 10.1007/s00268-009-0007-5. View

3.
Sabbagh C, Chatelain D, Trouillet N, Mauvais F, Bendjaballah S, Browet F . Does use of a metallic colon stent as a bridge to surgery modify the pathology data in patients with colonic obstruction? A case-matched study. Surg Endosc. 2013; 27(10):3622-31. DOI: 10.1007/s00464-013-2934-3. View

4.
van Hooft J, van Halsema E, Vanbiervliet G, Beets-Tan R, DeWitt J, Donnellan F . Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. Endoscopy. 2014; 46(11):990-1053. DOI: 10.1055/s-0034-1390700. View

5.
Deans G, Krukowski Z, Irwin S . Malignant obstruction of the left colon. Br J Surg. 1994; 81(9):1270-6. DOI: 10.1002/bjs.1800810905. View