Long-term Side Effects of Glucocorticoids

Overview

Journal Expert Opin Drug Saf

Specialty Pharmacology

Date 2016 Jan 21

PMID 26789102

Citations 301

Authors

Merih Oray

Khawla Abu Samra

Nazanin Ebrahimiadib

Halea Meese

C Stephen Foster

Affiliations

Soon will be listed here.

Abstract

Introduction: Glucocorticoids represent the standard therapy for reducing inflammation and immune activation in various diseases. However, as with any potent medication, they are not without side effects. Glucocorticoid-associated side effects may involve most major organ systems. Musculoskeletal, gastrointestinal, cardiovascular, endocrine, neuropsychiatric, dermatologic, ocular, and immunologic side effects are all possible.

Areas Covered: This article analyzes English-language literature and provides an update on the most recent literature regarding side effects of systemic glucocorticoid treatment.

Expert Opinion: The risk/benefit ratio of glucocorticoid therapy can be improved by proper use. Careful monitoring and using appropriate preventive strategies can potentially minimize side effects.

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