Genetic Polymorphisms Associated with Heart Failure: A Literature Review

Overview

Journal J Int Med Res

Publisher Sage Publications

Specialty General Medicine

Date 2016 Jan 16

PMID 26769713

Citations 7

Authors

Mengqi Guo

Guanlun Guo

Xiaoping Ji

Affiliations

Soon will be listed here.

Abstract

Objective: To review possible associations reported between genetic variants and the risk, therapeutic response and prognosis of heart failure.

Methods: Electronic databases (PubMed, Web of Science and CNKI) were systematically searched for relevant papers, published between January 1995 and February 2015.

Results: Eighty-two articles covering 29 genes and 39 polymorphisms were identified.

Conclusion: Genetic association studies of heart failure have been highly controversial. There may be interaction or synergism of several genetic variants that together result in the ultimate pathological phenotype for heart failure.

Citing Articles

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The Genetic Variants in the Renin-Angiotensin System and the Risk of Heart Failure in Polish Patients.

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Clinical impact of echocardiography parameters and molecular biomarkers in heart failure: Correlation of and polymorphisms with echocardiography parameters: A comparative study.

Suciu-Petrescu M, Truta A, Suciu M, Trifa A, Petrescu D, Rosianu H Exp Ther Med. 2021; 22(1):686.

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