Mean Platelet Volume in Early Diagnosis of Adnexal Torsion

Overview

Journal Balkan Med J

Publisher Galenos Publishing House

Specialty General Medicine

Date 2016 Jan 8

PMID 26740902

Citations 4

Authors

Isil Koleli

Affiliations

Soon will be listed here.

Abstract

Background: Adnexal torsion (AT) is among the gynecological emergencies; more common in reproductive age, if diagnosed late, this can cause ovarian failure and infertility, but rarely thrombophlebitis and peritonitis. Despite these severe complications, preoperative diagnostic tests are not enough for early diagnosis. There are certain pieces of literature on the subject that reveal changes in mean platelet volume (MPV) values occur in inflammatory and ischemic diseases and that these changes have diagnostic and prognostic significance. However, there are no studies investigating this relationship with adnexal torsion.

Aims: The aim of the study is to investigate the diagnostic and prognostic significance of the mean platelet volume value in the early diagnosis of patients with adnexal torsion.

Study Design: Case-control study.

Methods: Pre-operative demographic data, MPV, leukocyte count and neutrophils to lymphocytes (N/L) ratio in the blood samples of 51 patients, who were operated on preliminary adnexal torsion and diagnosed as adnexal torsion with a benign ovarian cyst (AT group) were retrospectively compared with those of 50 patients who were operated upon because of benign ovarian cysts and without torsion (control group) at this hospital between 2006 and 2014.

Results: The mean MPV level was found to be 8.1 (7.1-10.7) fL in the AT group and 7.9 (6.6-10.2) fL in the control group; no statistically significant difference was found between the groups (p>0.05). Leukocyte count and N/L ratio in the AT group were, on average, 12×10(3)/mm(3) and 82% respectively and in control group; they were, on average, 7.2×10(3)/mm(3) and 59%, respectively. A statistically significant increase was found in the leukocyte count and N/L ratio of the AT group compared to the control group (p<0.001). The platelet count in the AT group was, on average, 253×10(3)/mm(3) and in the control group it was, on average, 280×10(3)/mm(3); no statistically significant difference was detected between these two groups (p>0.05). No correlation was detected between the MPV, platelet and leukocyte counts. The sensitivity of the leukocytosis to the AT cases was found to be 66.7%, and selectivity was 94%.

Conclusion: The AT diagnostic and prognostic importance of MPV value has not been determined in this study.

Citing Articles

Predictive Role of Neutrophil to Lymphocyte Ratio in Adnexal Torsion: A Systematic Review and Meta-Analysis.

Khanzadeh S, Tahernia H, Hernandez J, Sarcone C, Lucke-Wold B, Salimi A Mediators Inflamm. 2022; 2022:9680591.

PMID: 36387932 PMC: 9649322. DOI: 10.1155/2022/9680591.

Diagnostic value of neutrophil to lymphocyte ratio in differentiation of ruptured ovarian cysts and adnexal torsion.

Soysal S, Baki R Turk J Obstet Gynecol. 2018; 15(2):91-94.

PMID: 29971185 PMC: 6022430. DOI: 10.4274/tjod.95881.

Effects of Apigenin on Experimental Ischemia/Reperfusion Injury in the Rat Ovary.

Soyman Z, Kelekci S, Sal V, Sevket O, Bayindir N, Uzun H Balkan Med J. 2017; 34(5):444-449.

PMID: 28443590 PMC: 5635632. DOI: 10.4274/balkanmedj.2016.1386.

Comorbidities must Be Considered in Mean Platelet Volume Measurements in Patients with Adnexial Torsion.

Varol E Balkan Med J. 2016; 33(4):482.

PMID: 27606151 PMC: 5001833. DOI: 10.5152/balkanmedj.2016.16107.

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