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Gastric Bypass in Older Patients: Complications, Weight Loss, and Resolution of Comorbidities at 2 Years in a Matched Controlled Study

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Journal Obes Surg
Date 2016 Jan 8
PMID 26738894
Citations 6
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Abstract

Background: Roux-en-Y gastric bypass (RYGB) has recently been authorized for use in older patients. The objective of this single-center study was to evaluate 2-year weight loss in patients ≥60 years compared with younger matched patients undergoing RYGB. Secondary aims were to record complications and the resolution of comorbidities in a 2-year follow-up.

Methods: Of 722 patients with at least 2 years follow-up data, 48 elderly patients were matched with 92 young (<40 years) and 96 middle-aged (40-59 year) patients, according to sex, baseline body mass index, and date of surgery. Weight loss, remission of comorbidities, death, and early (30-day) and 2-year complication rates were compared.

Results: There were three deaths in the elderly group and none in the other groups. The early complication rate was not significantly different in the elderly group (17.8 %) compared with the young (11.5 %, p = 0.637) and middle-aged (13.7 %, p = 1.000) groups. The 2-year complication rates were not significantly different in the elderly group (9.3 %) compared with the young (23.5 %, p = 0.107) and middle-aged (13.2 %, p = 1.000) groups. The 2-year weight loss was lower in the elderly group (31.8 ± 7.2 %; p < 0.001) than in the young group (38.3 ± 6.9 %) but was not significantly different from that in the middle-aged group (34.4 ± 8.0 %; p = 0.145). Remission rates for diabetes and obstructive sleep apnea were lower in the elderly than in the two younger groups.

Conclusion: After bariatric surgery, major weight loss was observed in patients older than 60, but remission of metabolic comorbidities was less marked than in younger subjects.

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References
1.
Witham M, Avenell A . Interventions to achieve long-term weight loss in obese older people: a systematic review and meta-analysis. Age Ageing. 2010; 39(2):176-84. DOI: 10.1093/ageing/afp251. View

2.
Dunkle-Blatter S, St Jean M, Whitehead C, Strodel 3rd W, Bennotti P, Still C . Outcomes among elderly bariatric patients at a high-volume center. Surg Obes Relat Dis. 2007; 3(2):163-9. DOI: 10.1016/j.soard.2006.12.004. View

3.
Willkomm C, Fisher T, Barnes G, Kennedy C, Kuhn J . Surgical weight loss >65 years old: is it worth the risk?. Surg Obes Relat Dis. 2010; 6(5):491-6. DOI: 10.1016/j.soard.2009.09.020. View

4.
Buse J, Caprio S, Cefalu W, Ceriello A, Del Prato S, Inzucchi S . How do we define cure of diabetes?. Diabetes Care. 2009; 32(11):2133-5. PMC: 2768219. DOI: 10.2337/dc09-9036. View

5.
Messier S, Loeser R, Miller G, Morgan T, Rejeski W, Sevick M . Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial. Arthritis Rheum. 2004; 50(5):1501-10. DOI: 10.1002/art.20256. View