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Factors Associated With the Development of Chronic Post-Sternotomy Pain: a Case-Control Study

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Date 2016 Jan 7
PMID 26735602
Citations 8
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Abstract

Objective: The aim of the present study was to investigate the factors associated with chronic post-sternotomy pain in heart surgery patients.

Methods: Between January 2013 and February 2014, we evaluated 453 patients with >6 months post-sternotomy for cardiac surgery at a surgical outpatient clinic. The patients were allocated into a group with chronic post-sternotomy pain (n=178) and a control group without pain (n=275). The groups were compared for potential predictors of chronic post-sternotomy pain. We used Cox proportional hazards regression to determine which independent variables were associated with the development of chronic post-sternotomy pain.

Results: In total, 39.29% of the patients had chronic poststernotomy pain. The following factors were significantly associated with chronic post-sternotomy pain: (a) use of the internal thoracic artery in coronary bypass grafting (P =0.009; HR=1.39; 95% CI, 1.08 to 1.80); (b) a history of antidepressant use (P =0.0001; HR=2.40; 95% CI, 1.74 to 3.32); (c) hypothyroidism (P =0.01; HR=1.27; 95% CI, 1.03 to 1.56); (d) surgical wound complication (P =0.01; HR=1.69; 95% CI, 1.08 to 2.63), and (e) patients on disability benefits or scheduled for a consultative medical examination for retirement (P =0.0002; HR=2.05; 95% CI, 1.40 to 3.02).

Conclusion: The factors associated with chronic poststernotomy pain were: use of the internal thoracic artery; use of antidepressants; hypothyroidism; surgical wound complication, and patients on disability benefits or scheduled for a consultative examination.

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References
1.
Macrae W . Chronic pain after surgery. Br J Anaesth. 2001; 87(1):88-98. DOI: 10.1093/bja/87.1.88. View

2.
van Gulik L, Janssen L, Ahlers S, Bruins P, Driessen A, van Boven W . Risk factors for chronic thoracic pain after cardiac surgery via sternotomy. Eur J Cardiothorac Surg. 2011; 40(6):1309-13. DOI: 10.1016/j.ejcts.2011.03.039. View

3.
Mailis A, Chan J, Basinski A, Feindel C, Vanderlinden G, Taylor A . Chest wall pain after aortocoronary bypass surgery using internal mammary artery graft: a new pain syndrome?. Heart Lung. 1989; 18(6):553-8. View

4.
Alston R, Pechon P . Dysaesthesia associated with sternotomy for heart surgery. Br J Anaesth. 2005; 95(2):153-8. DOI: 10.1093/bja/aei152. View

5.
Steegers M, Snik D, Verhagen A, van der Drift M, Wilder-Smith O . Only half of the chronic pain after thoracic surgery shows a neuropathic component. J Pain. 2008; 9(10):955-61. DOI: 10.1016/j.jpain.2008.05.009. View