Orthogonal Chemical Functionalization of Patterned Gold on Silica Surfaces

Overview

Journal Beilstein J Nanotechnol

Specialty Biotechnology

Date 2016 Jan 7

PMID 26734519

Citations 1

Authors

Francisco Palazon

Didier Leonard

Thierry Le Mogne

Francesca Zuttion

Celine Chevalier

Magali Phaner-Goutorbe

Eliane Souteyrand

Yann Chevolot

Jean-Pierre Cloarec

Affiliations

Soon will be listed here.

Abstract

Single-step orthogonal chemical functionalization procedures have been developed with patterned gold on silica surfaces. Different combinations of a silane and a thiol were simultaneously deposited on a gold/silica heterogeneous substrate. The orthogonality of the functionalization (i.e., selective grafting of the thiol on the gold areas and the silane on the silica) was demonstrated by X-ray photoelectron spectroscopy (XPS) as well as time-of-flight secondary ion mass spectrometry (ToF-SIMS) mapping. The orthogonal functionalization was used to immobilize proteins onto gold nanostructures on a silica substrate, as demonstrated by atomic force microscopy (AFM). These results are especially promising in the development of future biosensors where the selective anchoring of target molecules onto nanostructured transducers (e.g., nanoplasmonic biosensors) is a major challenge.

Citing Articles

Spatially-Localized Functionalization on Nanostructured Surfaces for Enhanced Plasmonic Sensing Efficacy.

Bryche J, Vega M, Tempez A, Brule T, Carlier T, Moreau J Nanomaterials (Basel). 2022; 12(20).

PMID: 36296775 PMC: 9609756. DOI: 10.3390/nano12203586.

References

Priest C, Stevens N, Sedev R, Skinner W, Ralston J . Inferring wettability of heterogeneous surfaces by ToF-SIMS. J Colloid Interface Sci. 2008; 320(2):563-8. DOI: 10.1016/j.jcis.2008.01.042. View

Bellon S, Buchmann W, Gonnet F, Jarroux N, Anger-Leroy M, Guillonneau F . Hyphenation of surface plasmon resonance imaging to matrix-assisted laser desorption ionization mass spectrometry by on-chip mass spectrometry and tandem mass spectrometry analysis. Anal Chem. 2009; 81(18):7695-702. DOI: 10.1021/ac901140m. View

Morel A, Volmant R, Methivier C, Krafft J, Boujday S, Pradier C . Optimized immobilization of gold nanoparticles on planar surfaces through alkyldithiols and their use to build 3D biosensors. Colloids Surf B Biointerfaces. 2010; 81(1):304-12. DOI: 10.1016/j.colsurfb.2010.07.021. View

Sam S, Touahir L, Salvador Andresa J, Allongue P, Chazalviel J, Gouget-Laemmel A . Semiquantitative study of the EDC/NHS activation of acid terminal groups at modified porous silicon surfaces. Langmuir. 2009; 26(2):809-14. DOI: 10.1021/la902220a. View

Wang C, Yan Q, Liu H, Zhou X, Xiao S . Different EDC/NHS activation mechanisms between PAA and PMAA brushes and the following amidation reactions. Langmuir. 2011; 27(19):12058-68. DOI: 10.1021/la202267p. View

Laibinis P, Hickman J, Wrighton M, Whitesides G . Orthogonal self-assembled monolayers: alkanethiols on gold and alkane carboxylic acids on alumina. Science. 1989; 245(4920):845-7. DOI: 10.1126/science.245.4920.845. View

Caipa Campos M, Trilling A, Yang M, Giesbers M, Beekwilder J, Paulusse J . Self-assembled functional organic monolayers on oxide-free copper. Langmuir. 2011; 27(13):8126-33. DOI: 10.1021/la200932w. View

Bedford E, Boujday S, Humblot V, Gu F, Pradier C . Effect of SAM chain length and binding functions on protein adsorption: β-lactoglobulin and apo-transferrin on gold. Colloids Surf B Biointerfaces. 2014; 116:489-96. DOI: 10.1016/j.colsurfb.2014.01.031. View

Brito e Abreu S, Skinner W . Determination of contact angles, silane coverage, and hydrophobicity heterogeneity of methylated quartz surfaces using ToF-SIMS. Langmuir. 2012; 28(19):7360-7. DOI: 10.1021/la300352f. View

10.

Dodson S, Haggui M, Bachelot R, Plain J, Li S, Xiong Q . Optimizing Electromagnetic Hotspots in Plasmonic Bowtie Nanoantennae. J Phys Chem Lett. 2015; 4(3):496-501. DOI: 10.1021/jz302018x. View

11.

Halpern A, Chen Y, Corn R, Kim D . Surface plasmon resonance phase imaging measurements of patterned monolayers and DNA adsorption onto microarrays. Anal Chem. 2011; 83(7):2801-6. PMC: 3108464. DOI: 10.1021/ac200157p. View

12.

Wegner G, Lee H, Corn R . Characterization and optimization of peptide arrays for the study of epitope-antibody interactions using surface plasmon resonance imaging. Anal Chem. 2002; 74(20):5161-8. DOI: 10.1021/ac025922u. View

13.

Lalander C, Zheng Y, Dhuey S, Cabrini S, Bach U . DNA-directed self-assembly of gold nanoparticles onto nanopatterned surfaces: controlled placement of individual nanoparticles into regular arrays. ACS Nano. 2010; 4(10):6153-61. DOI: 10.1021/nn101431k. View

14.

Feuz L, Jonsson P, Jonsson M, Hook F . Improving the limit of detection of nanoscale sensors by directed binding to high-sensitivity areas. ACS Nano. 2010; 4(4):2167-77. DOI: 10.1021/nn901457f. View

15.

Kumar K, Dahlin A, Sannomiya T, Kaufmann S, Isa L, Reimhult E . Embedded plasmonic nanomenhirs as location-specific biosensors. Nano Lett. 2013; 13(12):6122-9. DOI: 10.1021/nl403445f. View

16.

Khoury G, Laurenceau E, Chevolot Y, Souteyrand E, Cloarec J . A generic surface chemistry for peptide microarrays implementation: application to the detection of anti-H3 antibody. Biosens Bioelectron. 2010; 26(4):1320-5. DOI: 10.1016/j.bios.2010.07.032. View

17.

Palazon F, Rojo-Romeo P, Chevalier C, Gehin T, Belarouci A, Cornillon A . Nanoparticles selectively immobilized onto large arrays of gold micro and nanostructures through surface chemical functionalizations. J Colloid Interface Sci. 2014; 447:152-8. DOI: 10.1016/j.jcis.2014.11.028. View

18.

Zhang N, Liu Y, Yang J, Su X, Deng J, Chum C . High sensitivity molecule detection by plasmonic nanoantennas with selective binding at electromagnetic hotspots. Nanoscale. 2013; 6(3):1416-22. DOI: 10.1039/c3nr04494g. View

19.

Canepa M, Maidecchi G, Toccafondi C, Cavalleri O, Prato M, Chaudhari V . Spectroscopic ellipsometry of self assembled monolayers: interface effects. The case of phenyl selenide SAMs on gold. Phys Chem Chem Phys. 2013; 15(27):11559-65. DOI: 10.1039/c3cp51304a. View

20.

Palazon F, Benavides C, Leonard D, Souteyrand E, Chevolot Y, Cloarec J . Carbodiimide/NHS derivatization of COOH-terminated SAMs: activation or byproduct formation?. Langmuir. 2014; 30(16):4545-50. DOI: 10.1021/la5004269. View