» Articles » PMID: 26705442

Febrile Exanthem with Hyperferritinemia

Overview
Date 2015 Dec 26
PMID 26705442
Authors
Affiliations
Soon will be listed here.
Abstract

Diagnosis of an adult with acute generalized exanthem coupled with spiking fevers, arthralgias, and myalgias requires careful consideration. History and physical examination are basic necessities, while laboratory studies can be valuable adjuncts. The authors present a case of adult onset Still's disease, discuss the differential diagnoses, and highlight the utility of high serum ferritin in identifying this febrile exanthem.

References
1.
Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H . Preliminary criteria for classification of adult Still's disease. J Rheumatol. 1992; 19(3):424-30. View

2.
Fautrel B, Zing E, Golmard J, Le Moel G, Bissery A, Rioux C . Proposal for a new set of classification criteria for adult-onset still disease. Medicine (Baltimore). 2002; 81(3):194-200. DOI: 10.1097/00005792-200205000-00003. View

3.
Meijvis S, Endeman H, Geers A, ter Borg E . Extremely high serum ferritin levels as diagnostic tool in adult-onset Still's disease. Neth J Med. 2007; 65(6):212-4. View

4.
Tran T, Eubanks S, Schaffer K, Zhou C, Linder M . Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron. Blood. 1998; 90(12):4979-86. View

5.
Wang J, Pantopoulos K . Regulation of cellular iron metabolism. Biochem J. 2011; 434(3):365-81. PMC: 3048577. DOI: 10.1042/BJ20101825. View