[Experimental Study on the Immunosuppressive Effects of Gui Zhi Tang]

Overview

Journal Zhong Xi Yi Jie He Za Zhi

Specialty Rehabilitation Medicine

Date 1989 May 1

PMID 2670285

Citations 2

Authors

X F Lu

Affiliations

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Abstract

In this paper the immunosuppressive effects of Gui Zhi Tang (a famous Chinese medicine) on the murine immune functions are reported. Varying dosages of Gui Zhi Tang administrated orally, i.p. and i.m. were able to inhibit the amounts of PFC, SRFC and the DTH response induced by BSA and the proliferation response of murine spleen cells to Con A and LPS. Further studies showed that Gui Zhi Tang had the inhibitory effect on Interleukin-2 production of murine spleen cells, which might be one of the mechanisms leading to the immunosuppressive effects of Gui Zhi Tang.

Citing Articles

Inhibitory Effects of Gyeji-Tang on MMP-9 Activity and the Expression of Adhesion Molecules in IL-4- and TNF-α-Stimulated BEAS-2B Cells.

Kim Y, Jeon W, Hwang Y, Lee M Plants (Basel). 2021; 10(5).

PMID: 34068739 PMC: 8151808. DOI: 10.3390/plants10050951.

Effect of Gui Zhi decoction on enteric mucosal immune in mice with collagen-induced arthritis.

Zhou G, Zhao N, Zhang H, Jia H, Zhang W, Zhao L World J Gastroenterol. 2005; 11(34):5373-6.

PMID: 16149149 PMC: 4622812. DOI: 10.3748/wjg.v11.i34.5373.