Clinical Effectiveness and Cost-effectiveness of the Rehabilitation Enablement in Chronic Heart Failure (REACH-HF) Facilitated Self-care Rehabilitation Intervention in Heart Failure Patients and Caregivers: Rationale and Protocol for a Multicentre...

Overview

Journal BMJ Open

Specialty General Medicine

Date 2015 Dec 25

PMID 26700291

Citations 23

Authors

R S Taylor

C Hayward

V Eyre

J Austin

R Davies

P Doherty

K Jolly

J Wingham

R Van Lingen

C Abraham

C Green

F C Warren

N Britten

C J Greaves

S Singh

S Buckingham

K Paul

H Dalal

Affiliations

Soon will be listed here.

Abstract

Introduction: The Rehabilitation EnAblement in CHronic Heart Failure (REACH-HF) trial is part of a research programme designed to develop and evaluate a health professional facilitated, home-based, self-help rehabilitation intervention to improve self-care and health-related quality of life in people with heart failure and their caregivers. The trial will assess the clinical effectiveness and cost-effectiveness of the REACH-HF intervention in patients with systolic heart failure and impact on the outcomes of their caregivers.

Methods And Analysis: A parallel two group randomised controlled trial with 1:1 individual allocation to the REACH-HF intervention plus usual care (intervention group) or usual care alone (control group) in 216 patients with systolic heart failure (ejection fraction <45%) and their caregivers. The intervention comprises a self-help manual delivered by specially trained facilitators over a 12-week period. The primary outcome measure is patients' disease-specific health-related quality of life measured using the Minnesota Living with Heart Failure questionnaire at 12 months' follow-up. Secondary outcomes include survival and heart failure related hospitalisation, blood biomarkers, psychological well-being, exercise capacity, physical activity, other measures of quality of life, patient safety and the quality of life, psychological well-being and perceived burden of caregivers at 4, 6 and 12 months' follow-up. A process evaluation will assess fidelity of intervention delivery and explore potential mediators and moderators of changes in health-related quality of life in intervention and control group patients. Qualitative studies will describe patient and caregiver experiences of the intervention. An economic evaluation will estimate the cost-effectiveness of the REACH-HF intervention plus usual care versus usual care alone in patients with systolic heart failure.

Ethics And Dissemination: The study is approved by the North West-Lancaster Research Ethics Committee (ref 14/NW/1351). Findings will be disseminated via journals and presentations to publicise the research to clinicians, commissioners and service users.

Trial Registration Number: ISRCTN86234930; Pre-results.

Citing Articles

Exercise-based cardiac rehabilitation for adults with heart failure.

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Social network interventions to support cardiac rehabilitation and secondary prevention in the management of people with heart disease.

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Home-based cardiac rehabilitation and physical activity in people with heart failure: a secondary analysis of the REACH-HF randomised controlled trials.

Dibben G, Hillsdon M, Dalal H, Tang L, Doherty P, Taylor R BMJ Open. 2023; 13(2):e063284.

PMID: 36759035 PMC: 9923308. DOI: 10.1136/bmjopen-2022-063284.

Methodological approaches to study context in intervention implementation studies: an evidence gap map.

Mielke J, Brunkert T, Zuniga F, Simon M, Zullig L, de Geest S BMC Med Res Methodol. 2022; 22(1):320.

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Why Do so Few People with Heart Failure Receive Cardiac Rehabilitation?.

Thompson D, Ski C, Clark A, Dalal H, Taylor R Card Fail Rev. 2022; 8:e28.

PMID: 36303590 PMC: 9585646. DOI: 10.15420/cfr.2022.16.

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