Resveratrol and Omega-3 Fatty Acid: Its Implications in Cardiovascular Diseases

Overview

Journal Front Cardiovasc Med

Specialty Cardiology & Vascular Diseases

Date 2015 Dec 24

PMID 26697434

Citations 11

Authors

Bibhuti Bhusan Kakoti

Diana G Hernandez-Ontiveros

Manjir Sarma Kataki

Kajri Shah

Yashwant Pathak

Siva Kumar Panguluri

Affiliations

Soon will be listed here.

Abstract

The present review aims at summarizing the major therapeutic roles of resveratrol and omega-3 fatty acids (O3FAs) along with their related pathways. This article reviews some of the key studies involving the health benefits of resveratrol and O3FAs. Oxidative stress has been considered as one of the most important pathophysiological factors associated with various cardiovascular disease conditions. Resveratrol, with the potent antioxidant and free radical scavenging properties, has been proven to be a significantly protective compound in restoring the normal cardiac health. A plethora of research also demonstrated the reduction of the risk of coronary heart disease, hypertension, and stroke, and their complications by O3FAs derived from fish and fish oils. This review describes the potential cardioprotective role of resveratrol and O3FAs in ameliorating the endoplasmic reticulum stress.

Citing Articles

Therapeutic effects of resveratrol and Omega-3 in mice atherosclerosis: focus on histopathological changes.

Mosavi S, Rabizadeh S, Yadegar A, Seifouri S, Mohammadi F, Qahremani R BMC Complement Med Ther. 2023; 23(1):81.

PMID: 36932392 PMC: 10024363. DOI: 10.1186/s12906-023-03899-9.

Influence of nanoemulsion/gum ratio on droplet size distribution, rheology and physical stability of nanoemulgels containing inulin and omega-3 fatty acids.

Alfaro-Rodriguez M, Prieto P, Garcia M, Martin-Pinero M, Munoz J J Sci Food Agric. 2022; 102(14):6397-6403.

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A comparative study of biological potentiality and EAC cell growth inhibition activity of (L.) fruit pulp and seed in Bangladesh.

Shimu A, Miah M, Billah M, Karmakar S, Mohanto S, Khatun R Saudi J Biol Sci. 2021; 28(3):2014-2022.

PMID: 33732088 PMC: 7938185. DOI: 10.1016/j.sjbs.2021.01.004.

Resveratrol Modulates the Inflammatory Profile of Immune Responses and Circulating Endothelial Cells' (CECs') Population During Acute Whole Body Gamma Irradiation.

Khalil A, Al-Massarani G, Aljapawe A, Ekhtiar A, Bakir M Front Pharmacol. 2020; 11:528400.

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The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection.

Oppedisano F, Macri R, Gliozzi M, Musolino V, Carresi C, Maiuolo J Biomedicines. 2020; 8(9).

PMID: 32854210 PMC: 7554783. DOI: 10.3390/biomedicines8090306.

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